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ACE-031 is a soluble peptide derived from activin receptor type IIB (ActRIIB), primarily known for its role in promoting muscle growth. It achieves this by inhibiting myostatin, a protein that restricts muscle development, along with other negative regulators of muscle mass [1].
This makes ACE-031 an intriguing option for enhancing muscle growth, particularly in conditions such as Duchenne Muscular Dystrophy (DMD), where improved muscle repair is crucial [2].
Buy ACE-031 Nasal Spray for research use from PharmaLabGlobal. Available in 15ml or 30 ml bottles here.
ACE-031 acts as a soluble form of the activin receptor type IIB (ActRIIB), playing a pivotal role in muscle growth regulation. It functions by binding to and inhibiting myostatin, a protein that naturally limits muscle growth [1].
Myostatin is part of a broader group of negative regulators that control muscle mass by signalling muscles to restrain excessive growth. When ACE-031 binds to these regulators, it blocks their activity, allowing muscles to grow larger and stronger. This disruption in the regulatory process can lead to enhanced muscle development, making ACE-031 particularly promising in addressing muscle-wasting conditions like Duchenne Muscular Dystrophy (DMD) [2].
By promoting muscle repair and growth, ACE-031 offers significant therapeutic potential, providing hope for improved treatment options for individuals suffering from muscle loss. Its ability to foster muscle health highlights its significance in both medical and athletic applications, marking a substantial step forward in muscle tissue enhancement and recovery therapies [3].
Buy ACE-031 Peptide Vial research product from PharmaLabGlobal. Available in 1 mg glass vials here.
When purchasing high purity ACE-031 from PharmaLabGlobal you will also require Bacteriostatic Water for peptide reconstitution. Find the full range of highest quality research consumables here.
Ace-031 peptide is a very specific peptide which could, with further research it could have the following potential applications:
Potential Treatment for Muscle Wasting Diseases
ACE-031 peptide offers promising benefits for individuals suffering from muscle-wasting diseases through its unique mechanism of action. By functioning as a soluble form of the activin receptor type IIB (ActRIIB), ACE-031 binds to myostatin and other negative regulators that typically limit skeletal muscle growth. This inhibition allows for increased muscle mass and strength, overcoming the natural restrictions placed by these proteins.
In conditions like Duchenne Muscular Dystrophy (DMD), where muscle deterioration is a significant concern, ACE-031’s ability to promote muscle repair and growth is particularly valuable [2].
By enhancing muscle development, ACE-031 can potentially improve the quality of life for patients, aiding in better physical function and overall mobility. Its therapeutic application extends beyond DMD, offering hope for other muscle-wasting conditions by fostering healthier, stronger muscle cells [1].
This peptide’s role in muscle repair and growth highlights its potential to transform treatment approaches and improve outcomes for those affected by these debilitating diseases.
Muscle Repair
Clinical studies have suggested that ACE-031 peptide can significantly aid athletes in muscle repair by leveraging its ability to inhibit myostatin and other negative regulators of muscle growth. By doing so, ACE-031 promotes enhanced muscle recovery and development, which is crucial for athletes who experience frequent muscle stress and strains. This peptide assists in faster recovery from injuries, thereby reducing downtime and allowing athletes to return to their training and competitions more quickly.
Furthermore, ACE-031 contributes to improved overall muscle health and performance, facilitating increased muscle strength and endurance. These benefits can lead to superior athletic performance, as athletes experience less fatigue and can endure longer periods of physical activity [3].
Enhances Bone Mineral Density
ACE-031, a myostatin inhibitor, can enhance bone density by positively influencing bone metabolism. Clinical studies have shown that ACE-031 improves bone mineral density, potentially benefiting bone health and strength. By blocking myostatin, it not only promotes muscle growth but also supports stronger, healthier bones.
Buy ACE-031 Pre-Mixed Peptide Pen. Pen kits and pre-mixed refill cartridges supplied by PharmaLabGlobal for research purposes.
Is ACE-031 a sports supplement?
No, ACE-031 is not a sports supplement and is not approved for human consumption by the FDA. Further research is required to establish the efficacy of ACE-031 before it is approved by the drug administration agency for the usage in clinical settings.
How can I store ACE-031 Peptide?
Short term storage of peptides should be in a refrigerator to maintain the integrity of the research compound. For long term storage of peptides, it’s best to keep them in lyophilized form at temperatures of -20°C or colder, ideally in a desiccator to protect them from moisture.
[1] Attie KM, Borgstein NG, Yang Y, Condon CH, Wilson DM, Pearsall AE, Kumar R, Willins DA, Seehra JS, Sherman ML. A single ascending-dose study of muscle regulator ACE-031 in healthy volunteers. Muscle Nerve. 2013 Mar;47(3):416-23.
[2] Campbell C, McMillan HJ, Mah JK, Tarnopolsky M, Selby K, McClure T, Wilson DM, Sherman ML, Escolar D, Attie KM. Myostatin inhibitor ACE-031 treatment of ambulatory boys with Duchenne muscular dystrophy: Results of a randomized, placebo-controlled clinical trial. Muscle Nerve. 2017 Apr;55(4):458-464.
[3] Mitra A, Qaisar R, Bose B, Sudheer SP. The elusive role of myostatin signaling for muscle regeneration and maintenance of muscle and bone homeostasis. Osteoporos Sarcopenia. 2023 Mar;9(1):1-7.
The Ultimate Guide to Muscle Building Peptides
This blog delves into the potential of muscle building peptides to enhance fitness by promoting lean muscle mass, increasing strength, and improving physique. It explains the mechanism of these peptides, which function by boosting growth hormone and IGF-1 levels in the body, thereby supporting muscle growth and recovery. The guide also examines different types of peptides, such as CJC-1295, GHRP-6, IGF-1, BPC-157, and TB-500, each offering unique benefits for muscle development and healing.
ACE-031 Nasal Spray: Unlocking Potential of Muscle Growth
The ground breaking ACE-031 Nasal Spray, which uses a recombinant human activin receptor type IIB fusion protein to inhibit myostatin and promote muscle growth. This innovative delivery method offers a convenient alternative to injections, effectively increasing muscle mass, enhancing athletic performance, and supporting recovery. The blog also addresses the ongoing research into its efficacy and outlines potential side effects, underscoring its role in advancing muscle-building therapies.
From Inhibition to Stimulation: Unravelling the Secrets of GDF-8 Myostatin
Explore the pivotal role of GDF-8 Myostatin in muscle development and regulation. Delve into how this protein functions as a crucial regulator of muscle mass, with potential therapeutic applications in combating muscle-wasting conditions, enhancing bone strength, and supporting weight management. The blog further discusses the mechanisms by which GDF-8 Myostatin influences muscle growth and recovery, and highlights ongoing research into myostatin inhibitors like ACE-031.
Peptides are manufactured to a purity standard of 99% (complex peptides are 98% pure or higher)
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