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ARA-290 Nasal Spray
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ARA-290 Pre-Mixed Pen 2mg
£11.26 – £38.26
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ARA290 Peptide Vial 2mg
£8.86 – £17.84
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What is ARA-290 ?

ARA-290 is a non-erythropoietic peptide derived from erythropoietin, offering promising therapeutic applications. Unlike erythropoietin, it lacks effects on red blood cell production, making it a safer alternative for targeted treatments.

ARA-290 has demonstrated potential in improving small fiber nerve damage, often associated with neuropathy, while also reducing inflammation and supporting tissue repair. Its ability to promote metabolic control, including glycemic and lipid regulation, further expands its use, especially in conditions like type 2 diabetes.

Additionally, ARA-290’s role in injury repair and pain relief underscores its versatility, providing hope for managing a range of neuropathic and inflammatory challenges effectively [1].

Molecular Formula: C51H84N16O21

Sequence: ZEQLERALNSS

Source: PubChem

Molecular Weight: 1257.3 g/mol

View the ARA 290 peptide HPLC Certificate here.

Potential Benefits of ARA-290

Research professionals have identified that ARA-290 could have the following benefits:
Addresses neuropathy by targeting small fiber nerve damage.
Promotes tissue repair, aiding recovery from injuries.
Reduces inflammation, supporting overall healing processes.
Improves metabolic control, including glycemic and lipid regulation, particularly in type 2 diabetes.
Provides relief from neuropathic and chronic pain.

Buy ARA-290 Peptide Vial here – Available in 2mg vials for research use. PharmaLabGlobal is one of the best locations to buy ARA-290 peptide therapy for clinical research.

You will require Bacteriostatic Water to reconstitute the ARA-290 Peptide vial. Find the full range of research supplies here.

How ARA-290 Works

Scientific findings have demonstrated that ARA-290 operates through the activation of the innate repair receptor (IRR), a receptor formed by the interaction of the β common receptor (βcR) and erythropoietin receptor (EPOR). This receptor plays a key role in the body’s repair and recovery mechanisms [2].

Unlike erythropoietin, ARA-290 is non-erythropoietic, meaning it does not stimulate red blood cell production. Instead, it focuses on reducing inflammation, an essential process for fostering healing and mitigating chronic damage. ARA-290’s activation of the IRR triggers anti-inflammatory pathways, which helps protect tissues from further damage while promoting repair [1].

This peptide has shown particular efficacy in addressing small fiber nerve damage, a hallmark of neuropathic conditions, by restoring nerve function and improving patient comfort. By minimizing inflammatory damage and supporting wound repair and tissue protection without affecting erythropoiesis, ARA-290 provides a targeted therapeutic option for managing conditions linked to nerve damage and inflammation.

Peptide Nasal Sprays are a convenient and painless way of researching ARA-290 peptide. Buy ARA-290 peptide nasal spray for laboratory purposes from PharmaLabGlobal.

Potential Applications of ARA-290

Clinical studies have found that the ARA-290 synthetic peptide that mimics the effects of erythropoietin, a hormone that regulates red blood cell production, this could have the following applications:

Reduces Neuropathic Pain

ARA-290 effectively addresses neuropathy by targeting small fiber nerve damage, a common feature of neuropathic conditions [1]. Its mechanism of action involves activating the innate repair receptor (IRR), which plays a central role in tissue recovery and nerve protection. By stimulating IRR, ARA-290 initiates anti-inflammatory pathways that reduce damage caused by chronic inflammation, a key contributor to nerve dysfunction. Additionally, it aids in restoring the function of damaged small fiber nerves, which are responsible for pain and sensory signals. This targeted action not only mitigates neuropathic pain but also supports overall nerve repair, offering hope for improved nerve health and patient comfort.

Promotes Tissue Repair and Reduces Inflammation

By engaging the IRR, ARA-290 triggers anti-inflammatory mechanisms that reduce tissue damage caused by chronic or acute inflammation. This reduction in inflammation creates an environment conducive to healing and recovery. Furthermore, ARA-290 enhances the regeneration of damaged tissues by protecting cells from further injury and supporting their repair mechanisms. Its ability to specifically target damaged sites without interfering with unrelated systems adds to its therapeutic potential. This precise action fosters improved tissue recovery and offers hope for treating various injuries [3].

Improves Insulin Sensitivity

ARA-290 improves metabolic control by leveraging its potent anti-inflammatory properties. Chronic inflammation is a key factor in disrupting metabolic processes and contributing to insulin resistance, a hallmark of type 2 diabetes. By activating the innate repair receptor (IRR), ARA-290 reduces systemic inflammation, which helps restore cellular function and improve insulin sensitivity. This reduction in insulin resistance not only aids in stabilizing blood sugar levels but also enhances overall metabolic balance. Additionally, its targeted approach minimizes potential side effects, making it a promising therapeutic option for managing metabolic conditions like type 2 diabetes while supporting long-term health and recovery [4].

Buy ARA-290 Pre-Mixed Peptide Pen. Pen kits and pre-mixed refill cartridges supplied by PharmaLabGlobal for research purposes.

FAQ’s about ARA-290

What is erythropoiesis?

Erythropoiesis is the process by which red blood cells (erythrocytes) are produced in the body. This process occurs primarily in the bone marrow and is essential for maintaining healthy levels of red blood cells, which are responsible for blood vessels transporting oxygen from the lungs to tissues and organs and carrying carbon dioxide back to the lungs for exhalation.

The process of erythropoiesis is regulated by a hormone called erythropoietin (EPO), which is produced by the kidneys in response to low oxygen levels in the blood. When oxygen levels drop, the kidneys release more EPO, which stimulates the bone marrow to produce and release more red blood cells.

Erythropoiesis involves several stages of cell development, starting with hematopoietic stem cells in the bone marrow. These stem cells differentiate into immature red blood cells (reticulocytes) and eventually mature into fully functional erythrocytes. This process ensures the body has a sufficient supply of red blood cells to meet its oxygen transport needs.

Scientific Research

[1] Dahan A, Brines M, Niesters M, Cerami A, van Velzen M. Targeting the innate repair receptor to treat neuropathy. Pain Rep. 2016 Aug 9;1(1):e566.

[2] Swartjes M, van Velzen M, Niesters M, Aarts L, Brines M, Dunne A, Cerami A, Dahan A. ARA 290, a peptide derived from the tertiary structure of erythropoietin, produces long-term relief of neuropathic pain coupled with suppression of the spinal microglia response. Mol Pain. 2014 Feb 16;10:13.

[3] Mohammed A. Al-Onaizi, Peter Thériault, Sarah Lecordier, Paul Prefontaine, Serge Rivest, Ayman ElAli, Early monocyte modulation by the non-erythropoietic peptide ARA 290 decelerates AD-like pathology progression, Brain, Behavior, and Immunity, Volume 99, 2022, Pages 363-382.

[4] Brines M, Dunne AN, van Velzen M, Proto PL, Ostenson CG, Kirk RI, Petropoulos IN, Javed S, Malik RA, Cerami A, Dahan A. ARA 290, a nonerythropoietic peptide engineered from erythropoietin, improves metabolic control and neuropathic symptoms in patients with type 2 diabetes. Mol Med. 2015 Mar 13;20(1):658-66.

Derived from erythropoietin (EPO), this peptide activates anti-inflammatory and tissue-protective pathways, offering benefits like improved glucose regulation, reduced oxidative stress, enhanced cholesterol profiles, and neuroprotective effects. It also promotes angiogenesis, reduces inflammation, and accelerates wound healing. While generally well-tolerated, minor side effects like nasal irritation may occur. Highlighting its potential in treating conditions like neuropathic pain and diabetes, the blog underscores ARA-290’s promise in revolutionizing healthcare.

Learn about ARA-290 Nasal Spray

The Potential Role of Peptides in Diabetes Management

This blog delves into the transformative role of peptides in diabetes management, highlighting their potential to improve insulin sensitivity, regulate glucose metabolism, and address underlying biochemical processes. It explores key peptides like MOTS-c, AMPK, AICAR, ARA-290, and FTPP, showcasing their benefits in enhancing metabolic control, reducing insulin resistance, and aiding weight management. By targeting specific pathways, these peptides offer innovative solutions for Type 1, Type 2, and gestational diabetes, paving the way for personalized and effective treatments.

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DISCLAIMER: All products sold by Pharma Lab Global are for research and laboratory use only. These products are not designed for use or consumption by humans or animals. They are not to be classified as a drug, food, cosmetic, or medicinal product and must not be mislabelled or used as such. By purchasing from our Website the buyer accepts and acknowledges the risks involved with handling of these products. All articles and product information provided on this Website are for informational and educational purposes only. Handling and use of these products should be restricted to suitably qualified professionals

Buy ARA-290

ARA-290 Nasal Spray

ARA-290 Pre-Mixed Pen 2mg

ARA290 Peptide Vial 2mg

What is ARA-290 ?

Potential Benefits of ARA-290

How ARA-290 Works

Potential Applications of ARA-290

FAQ’s about ARA-290

Scientific Research

Further Reading:

Buy ARA-290 from PharmaLabGlobal

Premium Quality Peptides

Global Supplier

Excellent Customer Service

Competitive Prices

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ARA-290 Nasal Spray

ARA-290 Pre-Mixed Pen 2mg

ARA290 Peptide Vial 2mg

What is ARA-290 ?

Potential Benefits of ARA-290

How ARA-290 Works

Potential Applications of ARA-290

FAQ’s about ARA-290

Scientific Research

Further Reading:

Buy ARA-290 from PharmaLabGlobal

Premium Quality Peptides

Global Supplier

Excellent Customer Service

Competitive Prices

FREQUENTLY ASKED QUESTIONS

Do you offer delivery insurance?

How do I cancel an order?

How long until delivery?

WE SUPPLY PRODUCTS ALL OVER THE WORLD - INCLUDING THE LIST BELOW.

Get in touch

Useful

Shipping partners

Do you offer
delivery insurance?

How do I
cancel an order?

How long
until delivery?