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IGF-1 The Lowdown: A Comprehensive Guide

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Insulin-like Growth Factor-1 (IGF-1) is a hormone that plays a crucial role in the growth and development of the body. It is naturally produced in the liver and released in response to the stimulation of Growth Hormone (GH). This hormone is essential for cell growth, tissue repair, and muscle hypertrophy.

What is IGF-1?

IGF-1 hormone is a peptide hormone that consists of 70 amino acids and is structurally similar to insulin. It is synthesized in the liver and released into the bloodstream in response to the stimulation of GH. The main function of IGF-1 is to promote cell growth, tissue repair, and muscle hypertrophy. It also plays a role in regulating blood sugar levels by increasing the uptake of glucose by cells.

A low IGF-1 level in elderly people is associated to both weakness and an increased risk of illness. Maintaining adequate levels of Insulin-like Growth Factor-1 throughout later life is essential to the preservation of bone density, muscular mass, and cognitive function.

For the most part of our adult lives, we should strive to keep our levels of insulin-like growth factor 1 relatively low. When we reach our eighties and beyond, we should increase the amount of protein we eat so that our IGF-1 does not become dangerously low. This will allow us to live longer.

To maintain healthy levels of insulin-like growth factor 1 throughout our lives, it is critical that we pay close attention to the foods we eat.

IGF-1 is a cell growth promoter that is essential during childhood because of its role in the development of the brain as well as the growth of the muscles and bones. Levels are at their highest throughout our teenage and early adult years, and then begin to gradually decrease as we get older. Growth hormone, or GH, is secreted by the pituitary gland and stimulates the creation of IGF-1 in the liver.

Benefits of IGF-1

  1. Muscle Growth and Repair: IGF-1 hormone plays a significant role in muscle hypertrophy, making it a popular supplement for bodybuilders and athletes. According to research, IGF-1 promotes the growth and repair of muscle tissue by increasing protein synthesis, which leads to increased muscle mass and strength.
  2. Anti-Aging: This peptide has been shown to have anti-aging properties, as it helps to maintain the health and vitality of cells. It stimulates the production of collagen and elastin, which helps to keep skin looking youthful and supple.
  3. Bone Density: IGF-1 also plays a crucial role in bone growth and density. It promotes the differentiation of bone cells, leading to an increase in bone density and strength.
  4. Fat Loss: Insulin-like Growth Factor 1 has been shown in research to promote fat loss by increasing the breakdown of stored fat and increasing the use of fat as an energy source.

Athletic Performance

IGF-1 has become increasingly popular in the world of athletics due to its potential to improve muscle growth and strength. However, IGF-1 is a banned substance in most professional sports leagues and organizations due to its performance-enhancing properties.

Anti-Aging

IGF-1 levels naturally decrease as we age, leading to a decline in muscle mass, bone density, and overall physical function. Many researchers believe that increasing levels through supplementation could help delay the aging process and improve overall health in older individuals.

Conclusion

IGF-1 is a powerful hormone with both benefits and drawbacks. While it can improve muscle growth, bone density, and overall physical function, it also comes with potential risks such as cancer growth and hypoglycemia.

References:

[1] https://pubmed.ncbi.nlm.nih.gov/ 10605625/

[2] Adipose tissue-derived stem cell secreted IGF-1 protects myoblasts from the negative effect of myostatin – PubMed (nih.gov)

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