Description
AICAR Pre-Mixed Pen 50mg
AICAR pre-mixed pen peptide (also known as AICA Ribonucleotide) is the analogue of adenosine monophosphate. It has been used to treat myocardial ischemia following a heart attack. Furthermore, AICA ribonucleotide is an antioxidant that may aid in the prevention of ageing. AICAR Pre-Mixed Pen 50mg is being researched for diabetes, auto-immune disorders, and other inflammatory conditions.
Specifications
Molecular Formula: C9H15N4O8P
Molecular Weight: 338.21 g/mol
Sequence: 5-amino-4-imidazole carboxamide ribotide
aminoimidazole carboxamide ribonucleotide
Size: 1 Single mixed cartridge | 2 Pre mixed cartridges | 3 Pre mixed cartridges | Pen kit with 1 pre mixed cartridge
Research
Muscle growth
Muscle fibres are the fundamental skeletal muscle unit. Muscle fibre types in animals have an impact on meat quality. As a result, AMPK protein activity was assessed in gastrocnemius (GS) muscle fibre composition, enzyme activity, and mRNA expression of muscle fibre type-related genes [1].
AICAR, among other things, increases muscular mass in the body. It is necessary for both muscle growth and muscular mass preservation. It has also been shown in studies to reduce muscle loss.
According to research, AICAR pre-mixed pen peptide could one day be used to treat muscle wasting diseases. Furthermore, strenuous exercise improves AICAR’s muscle growth outcomes.
Anti-inflammatory properties
According to recent research, AICAR is involved in cellular inflammation. AICAR is related to metformin, a long-used diabetes therapy that is effective in part because of its anti-inflammatory properties.
Asthma, hepatitis, colitis, and atherosclerosis are all protected against by the AICAR pre-mixed pen. In mouse experiments, AICAR pre mixed peptide was proven to lessen inflammation in colitis [2].
AICAR may potentially aid in the treatment of autoimmune illnesses and other inflammatory diseases.
Fertility
AICAR, an AMPK activator, has been found in research on goats, cats, and chickens, among other species, to increase sperm motility, fertilising capacity, and metabolism. [3]Â [4].
Heart disease
Inflammation is a major contributor to cardiovascular disease (CVD). Animal studies have shown that AICAR’s anti-inflammatory properties are so potent that it can help halt the onset of vascular diseases [5].
The researchers intended to explore what would happen if they administered a pre-mixed AICAR pen to atherosclerotic mouse models and monitored the consequences [6]. AICAR decreased the formation of vascular smooth muscle, resulting in a reduction in both short- and long-term difficulties related with stent implantation and placement, according to the findings.
According to the study’s findings, activating AICA ribonucleotide appears to decrease immune responses associated with atherosclerosis. Furthermore, bad cholesterol (LDL) accumulates in the bloodstream, triggering macrophage proliferation and, eventually, a heart attack. AICAR use can help prevent the spread of heart disease and heart attacks, as well as potentially lessen their incidence.
Insulin sensitivity
Extensive research on mice reveals that pre-mixed AICAR pen dosages, both high and low, reduce inflammation in adipose tissue, which stores energy as fat [7].
Insulin resistance is connected to inflammation in adipose tissue. Reduced inflammation leads to improved glucose control. AICA ribonucleotide, for example, controls inflammation in adipose tissue via SIRT1 and macrophages.
Obese monkeys lost weight and had better insulin resistance.
According to AICA ribonucleotide studies, both healthy and diabetic mice have reduced inflammatory responses. AICAR pre mixed peptide has been shown to improve insulin sensitivity and minimise inflammatory symptoms.
Summary
AICA ribonucleotide is a protein that modulates insulin receptors and enhances insulin sensitivity in muscle cells and is required for metabolic pathways and energy balance. AICAR peptide hormone has been shown in studies to fight cancer and protect the heart. It also prevents premature blood clotting. As a result, scientists wish to continue investigating this protein. Historically, doctors used AICAR pre-mixed peptide to maintain the blood flowing to the heart. However, the peptide AICA ribonucleotide has the potential to be used as a diabetes treatment due to its capacity to increase tissue metabolism. It accomplishes this by modifying the muscular composition of the body.
References
[1] https://www.tandfonline.com/doi/ full/10.1080/09712119.2021. 1889563
[2] https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC4398665/
[3] https://pubmed.ncbi.nlm.nih.gov/ 31079268/
[4] https://www.frontiersin.org/ articles/10.3389/fcell.2017.00025/ full
[5] https://www.frontiersin.org/ articles/10.3389/fphar.2021.7384 20/full
[6] https://www.sciencedirect.com/ science/article/pii/S002228281 3002277
[7] https://www.ncbi.nlm.nih.gov/pmc/ articles/PMC2692788/
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