B7-33 Pre-Mixed Pen 2mg Peptide

Description

B7-33 Pre-Mixed Pen 2mg Peptide

B7-33 pre-mixed pen peptide possesses potent anti-fibrotic properties, particularly for acute and chronic diseases such as heart failure, lung inflammation, kidney disease, fibrosis reduction is a significant research focus.

B7-33 peptide is a synthetically designed peptide analogous to the B-chain of relaxin-2. It selectively activates the relaxin family peptide receptor 1 (RXFP1) and has shown promising results in conferring acute cardioprotection and limiting adverse remodelling in mice with myocardial infarction-related injury.

In animal models of hypertension, B7-33 has been found to decrease blood pressure by activating RXFP1, leading to vasodilation and potentially serving as a therapeutic option for hypertension management. Additionally, B7-33 has demonstrated efficacy in reducing myocardial stiffness and airway reactivity, making it a potential treatment for conditions such as myocardial fibrosis and respiratory diseases.

The production of B7-33 as a single-chain peptide is relatively easier and cost-effective, making it an excellent candidate for further modification and development compared to similar peptides. Extensive research has shown that B7 33 reduces fibrosis and prolongs survival after injury. Besides that, it has been shown to reduce excessive scarring after cardiac injury in several studies. Some vascular disorders and preeclampsia of pregnancy have also demonstrated promising results.

Specifications

Sequence: VIKLSGRELVRAQIAISGM STWSKRSL

Size: 1 Single mixed cartridge | 2 Pre mixed cartridges | 3 Pre mixed cartridges | Pen kit with 1 pre mixed cartridge

B7-33 Pre-Mixed Pen Benefits

Reducing Fibrosis

Peptide B7 33 is an anti-fibrotic agent. Reducing fibrosis is a significant focus of research and investigation for acute and chronic diseases like heart failure, lung inflammation, and more. According to animal studies using mouse models, by cutting fibrosis by half in animals, B7-33 could be the first new treatment for heart failure [1].

Implanted Medical Devices

Using B7-33 to reduce foreign body response to implanted medical devices is also considered an additional use. Clinical trials have found that because it reduces the growth of fibrotic capsules around implanted devices by half, B7 33 opens up possibilities for new and better implantable medical devices in addition to expanding current ones’ usefulness [2].

Vasoprotective Effects

Although it is an anti-fibrotic peptide, B7-33 is much more than that. In addition, recent studies have found it has several other properties, including its ability to lower blood pressure and protect the cardiovascular system. There is also evidence from studies in preeclampsia animal models that B7 33 could be an effective treatment for this challenging disease, allowing more women to carry their developing fetus to term in a safe manner for both mother and child [3].

Summary

There are many benefits to this B7-33 peptide beyond is anti-fibrotic and anti inflammatory effects. Clinical trials have found it possesses the ability to prevent damage to blood vessels, beneficial in the management of preeclampsia, reduce high blood pressure and protect the cardiovascular system.

References

[1] https://pubmed.ncbi.nlm.nih.gov/ 32295457/

[2] https://pubmed.ncbi.nlm.nih.gov/ 31713411/

[3] https://www.ahajournals.org/doi/ 10.1161/hyp.74.suppl_1.P3042

Buy B7-33 Pre-mixed Pen

Pharma Lab Global is one of the best locations to purchase high purity B7-33 pre-mixed pen peptide for research use. Pharma Lab Global is a trusted supplier of peptides worldwide. You also have the option to buy B7-33 nasal peptide spray and buy B7-33 Peptide Vial. Buy from Pharma Lab Global today!

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