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DSIP is a neuropeptide that affects several endocrine and physiological processes in the CNS. To reduce oxidative stress and normalize myocardial contractility, DSIP is studied. It’s also being investigated as a potential treatment for major depression.

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DSIP Peptide Vial Description

DSIP is a neuropeptide that affects several endocrine and physiological processes in the CNS. To reduce oxidative stress and normalize myocardial contractility, Delta Sleep Inducing Peptide is studied. It’s also being investigated as a potential treatment for major depression.

Delta Sleep Inducing Peptide is a well-known nonapeptide used to treat insomnia and stress. For over 40 years, scientists have studied the effects of Delta Sleep Inducing Peptide on mice’s bodies, with promising results.

Delta sleep peptide protects against stress-induced metabolic disorders in mice and other animals. In addition, animal studies have shown it can improve physical performance and hormone levels.

DSIP is a sleep-inducing hormone produced in the pituitary, hypothalamus, and adrenal glands.

Delta Sleep Inducing Peptide Research findings


The effects of Delta sleep-inducing peptide on sleep were studied in 16 chronic insomniacs using a parallel-groups design with matched pairs. The research looked at sleep structure, sleep quality, and subjective tiredness [1].

Delta Sleep Inducing Peptide had better sleep efficiency and shorter sleep latency than placebo in objective sleep quality tests. In addition, the DSIP group improved on one measure of subjective tiredness.

However, according to data analysis, the significant statistical effects were weak and may have been due to a placebo group change incidentally. Therefore, it was concluded that treating chronic insomnia with DSIP for a short period is unlikely to be beneficial because none of the other measures changed.

At night, the body produces essential hormones and essential physiological processes. Many sleep aids and medications alter the period or length of time of these sleep cycles, which can be problematic. The disruption of these natural sleep cycles reduces the efficiency and quality of sleep. Delta Sleep Inducing Peptide has been proven not to disrupt sleep cycles in scientific trials [2].

Pain relief

In the short term, medications like NSAIDs and opiates work but have long-term devastating side effects, so researchers are eager to find a new analgesic that doesn’t have side effects [3].

A small DSIP mouse study found the peptide can substantially decrease pain perception and improve overall well being. It also helped eliminate withdrawal symptoms in mice who were dependent on painkillers.

The natural analgesic properties of Delta Sleep Inducing Peptide are demonstrated in rat studies and illustrate that DSIP provides significant pain relief [4].

Effects on metabolism

The metabolism of Delta Sleep Inducing Peptide was studied in hypoxic rats and was found to reduce stress-induced changes in mitochondrial monoamine oxidase A (MAO-A) activity and serotonin levels in rat brains. In addition, Delta Sleep Inducing Peptide analogues were tested for their ability to counteract hypoxia-induced changes in MAO-A activity and serotonin content.

In rats, it has been shown that Delta Sleep Inducing Peptide reduces metabolic disturbances caused by stress, such as mitochondrial redox switching. The latter is inefficient and toxic. Acute hypoxia-response DSIP may help treat conditions like stroke and heart attack. DSIP may also help prevent metabolic damage from oxygen deprivation by maintaining normal mitochondrial function.

These features make Delta Sleep Inducing Peptide a potent antioxidant that targets free radicals. Delta Sleep Inducing Peptide also protects mitochondrial function, reducing free radical production. This may make it an anti-ageing supplement, though more research is needed [5].

Chemical imbalances and depression

Scientists began studying Delta Sleep Inducing Peptide and its effects on chemical imbalances after learning that it can alter mitochondrial activity in hypoxic conditions [6]. Researchers concluded that the inhibition of MAO-A and serotonin by DSIP may influence the course of depression. Delta Sleep Inducing Peptide levels were found to be lower in depressed patients than in healthy controls [7].

A peptide involved in sleep cycling may also be involved in depression, given the strong link between sleep and depression. Delta Sleep Inducing Peptide normalization has not been used to treat depression. The peptide has been linked to HPA axis (hypothalamic-pituitary-adrenal) changes and suicidal behaviour [8].

Delta Sleep Inducing Peptide summary

Animal studies have shown that delta-sleep inducing peptide has many health benefits. However, more research is required on its safety for the FDA to approve it.


  1. https://pubmed.ncbi.nlm.nih.gov/1299794/
  2. https://www.sciencedirect.com/topics/neuroscience/delta-sleep-inducing-peptide
  3. https://pubmed.ncbi.nlm.nih.gov/6548970/
  4. https://pubmed.ncbi.nlm.nih.gov/2853064/
  5. https://pubmed.ncbi.nlm.nih.gov/12668217/
  6. https://pubmed.ncbi.nlm.nih.gov/7628639/
  7. https://www.tandfonline.com/doi/abs/10.3109/08039488509101959
  8. https://pubmed.ncbi.nlm.nih.gov/9606527/
Buy DSIP Peptide vial 5mg

Pharma Lab Global is one of the best locations to purchase high purity DSIP for research. Pharma Lab Global is a trusted supplier of peptides and sarms worldwide. You have the option to buy DSIP Nasal Spray and buy DSIP Pre Mixed peptide from here. Buy DSIP peptide vial 10mg from Pharma Lab Global today!

DSIP Specifications

Molecular Formula: C35H48N10O15
Sequence: H-Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu-OH
Physical Appearance: White Lyophilised Solid
Form: Sterile Filtered White Lyophilized
Solubility: Water Soluble
Storage: Peptides should be refrigerated at 4˚C or below for a period of up to 3 months.


All products listed on this website and provided through Pharma Labs Global are intended for medical research purposes only. Pharma Lab Global does not encourage or promote the use of any of these products in a personal capacity (i.e. human consumption), nor are the products intended to be used as a drug, stimulant or for use in any food products.

Additional information


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