Follistatin 344 Pre-Mixed Pen 1mg

Description

Follistatin 344 Pre-Mixed Pen 1mg

The completely synthetic equivalent of follistatin, which occurs naturally, is called follistatin-344 (FS344). Follistin suppresses the actions of myostatin, activin, and FSH (follicle-stimulating hormone), according to animal research. This promotes hypertrophy and hyperplasia of the muscles, reduces the creation of scars, and blocks some inflammatory reactions. Furthermore, the body can alter Follistatin-344 to create various forms of follistatin.

A substance called follistatin 344 peptide combats hair loss brought on by the creation of DHT. The peptide is believed to inhibit the body’s five alpha-reductase enzyme and the hormone DHT. This makes it possible for natural testosterone to be produced. The protein helps produce DHT, which harms hair follicles, by converting testosterone. It is also utilised as an anti-aging and treatment for ageing alopecia.

Specifications

Sequence: MVRARHQPGG LCLLLLLLCQ FMEDRSAQAG NCWLRQAKNG RCOVLYKTEL SKEECCSTGR LSTSWTEEDV NDNTLFKWMI FNGGAPNCIP CKETCENVDC GPGKKCRMNK KNKPRCVCAP DCSNITWKGP VCGLDGKTYR NECALLKARC KEOPELEVOY QGRCIORCRD VFCPGSSTCV VDCITNNAYCV TCNRICPEPA SSEQYLCGND GVTYSSACHL RKATCLLGRS IGLAYEGKCI KAKSCEDIQC TGGKKCLWDF KVGRGRCSLC DELCPDSKSD EPVCASDNAT YASECAMKEA ACSSGVLLEV KHSGSCNSIS EDTEEEEEDE DODYSFPISS ILEW
Molecular Formula: C1350H2153N405O433S39
Molecular weight: 3780 g/mol

Size: 1 Single mixed cartridge | 2 Pre mixed cartridges | 3 Pre mixed cartridges | Pen kit with 1 pre mixed cartridge

Research

According to research, follistatin-344 interacts with growth factor peptides such as myostatin and suppresses them. Myostatin controls and restricts the growth of muscles. Although myostatin is necessary for skeletal muscle fibrosis, an excess of it can lead to long-term diseases of the organs, tissues, and bone marrow.

Follistatin-344 prevents the secretion of follicle-stimulating hormone (FSH) and the degenerative effects of myostatin. Male mice with elevated FSH levels may exhibit abnormal testicular and hormone function. Moreover, this hormone may impede the growth and repair of muscles. But insufficient levels may impair the ability to procreate.

Recent studies revealed that FS344 more successfully reduced myostatin than Trichostatin A. (TSA). Furthermore, follistatin does not require daily dosage, whereas TSA does [1].

Muscle growth

In experiments, a high Follistatin 344 dosage increases muscle mass. Most studies on the FS344 peptide, however, have been conducted on animals. Therefore, the use of follistatin 344 pre-mixed pens is not yet the subject of formal study. According to one study, animals with an excess of follistatin and a deficiency of myostatin had 17% larger muscular fibres than animals in the control group. Follistatin 344 pre-mixed pen has effects on muscle growth that go beyond those of muscle blockers, according to studies.

Mice without myostatin, for instance, had twice as much muscle mass. On the other hand, muscle mass was four times more in the follistatin transgenic and inhibited myostatin group than in the placebo group.

Similar to how folistatin promotes muscle growth, a prenatal deficiency in this protein can result in decreased muscle mass, which can impact the development of organs, bones, and tissues. Furthermore, it has been demonstrated to influence mice’s normal hormonal activity  [2].

Hair growth

The pre-mixed Follistatin 344 pen could help with male baldness. While in use, the peptides are known to inhibit the effect of DHT, preventing the peptide from entering the bloodstream. After that, it will attach to DHT and stop it from functioning properly. This facilitates the binding of follistatin to DHT, preventing it from acting normally. Consequently, baldness could be avoided because the FS344 peptide simply inhibits the body’s creation of DHT.

It has been demonstrated that follistatin considerably accelerates the growth of hair in mice. Follistatin for hair loss enhanced total hair density by 20% and hair thickness by 13% in a small study involving 24 mice [3].

Fertility

Follistatin has been shown to boost fertility in both male and female mice. By inhibiting activins, FS-344 supports a healthy pregnancy and delivery while also preventing ageing of the reproductive system. Additionally, there is proof that this peptide helps lessen menopausal symptoms [4].

Follistatin 344 is also present in high-quality sperm. Follistatin 344 pre-mixed pen supplementation may thereby increase mouse male fertility [5]. There is evidence that follistatin 344 pre-mixed may increase both male and female fertility, despite a lack of studies on the topic.

Liver Protection

Follistatin 344 has been found to have beneficial effects on the liver. Studies have shown that hepatic follistatin can increase the basal metabolic rate and attenuate diet-induced obesity during hepatic insulin resistance. Follistatin has also been shown to alleviate hepatic steatosis in non-alcoholic fatty liver disease (NAFLD) via the mTOR-dependent pathway, reducing hyperlipidemia and hepatic de novo lipogenesis [6]. Additionally, follistatin gene delivery has been found to enhance muscle growth and recovery of the liver after tumor-removing surgery in rats. These findings suggest that follistatin 344 has potential protective effects on the liver and may be beneficial in certain liver conditions.

Summary

It has been demonstrated that Follistatin 344 pre-mixed pen 1 mg can increase muscle growth and increase the fertility of both male and female mice.

According to recent research, increasing follistatin levels in mice promotes stronger muscular growth and better general health. In conclusion, it has been discovered that this potential peptide increases muscle and enhances reproductive health.

References

[1] https://www.science.org/ doi/10.1126/scitranslmed.3000112

[2] https://www.pnas.org/ doi/full/10.1073/pnas.0709144105

[3] https://pubmed.ncbi.nlm.nih.gov/ 22052313/

[4] https://pubmed.ncbi.nlm.nih.gov/ 19696363/

[5] https://pubmed.ncbi.nlm.nih.gov/ 11275954/

[6] https://pubmed.ncbi.nlm.nih.gov/ 36906067/

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