FTPP Adipotide Peptide Vial Description
Adipotide, or FTPP, is an investigational weight loss therapy that targets fat cells’ blood supply.
Adipotide is a novel medicine that has shown considerable potential in obesity research. Adipotide peptide, originally developed to treat cancer, has shown promise in tests for reducing body weight.
Adipotide (also known as FTPP or pro-apoptotic peptide) destroys fat cells by cutting off their blood supply. Adipotide is selective because it can distinguish between fat cell blood vessels and blood vessels throughout the body. In studies on monkeys, adipotide not only helps them lose weight but also improves insulin sensitivity and reduces the consequences of type 2 diabetes.
FTPP Adipotide Research findings
Adipotide’s phase I clinical trials began in 2011 to assess the drug’s ability to kill fat cells. To test this theory, researchers used rhesus monkeys. They discovered that giving animals adipotide caused apoptosis in WAT blood vessels (white adipose tissue).
As a result, fat cells died due to a lack of blood supply, resulting in rapid weight loss, reduced BMI, and better insulin resistance. In addition, the adipotide medication led to weight loss and improved eating habits. Adipotide-treated monkeys ate less food than non-treated monkeys .
Adipotide may be delivered to fat cell blood vessels via the protein receptor prohibitin. Prohibitin is found in just two types of cells: white fat and cancer cells. Also, adipotide interacts with this protein. Assuming prohibitin is found only in fat vasculature and cancer tissue, it must then identify a fat-specific target for medicinal and diagnostic purposes .
Adipotide’s target molecule, prohibitin, has been linked to cancer . To grow and metastasize, cancer cells require a lot of blood supply. Targeting prohibitin in cancer cells may allow for advanced cancer therapies that do not harm surrounding tissues.
Glucose tolerance is a word used to describe elevated blood sugar levels. Blood tests are used to detect and confirm the problem. A glucose tolerance test involves consuming a quantity of sugar and then evaluating the blood sugar levels. Glucose tolerance is a surrogate for diabetes, with greater glucose tolerance signifying diabetes.
Exercising and dieting can help lower blood sugar levels, but it takes effort and commitment. Their effect also takes time. Uncontrolled hyperglycemia usually leads to type 2 diabetes, requiring medications like metformin and sometimes insulin. Adipotide is a peptide that quickly improves glucose tolerance without weight gain.
Also, adipotide reduces glucose tolerance without affecting weight, which is crucial. That is, it is necessary to lose fat, not weight. These results pave the possibility for new diabetic treatments and help explain how diabetes develops.
There is some debate over whether adipotide induces fat loss directly or whether it just reduces food consumption, which results in indirect fat loss. Most likely, adipotide is responsible for fat reduction on a direct basis. In supporting this concept, the peptide affects glucose tolerance without affecting fat cell density .
FTPP Adipotide Peptide summary
Adipotide is primarily studied for weight loss and diabetes. The protein specifically targets cells in fat-supply blood vessels, killing them and the fat cells they supply. FTPP Adipotide targets blood vessels and is known as an anti-angiogenic peptide. Anti-angiogenic compounds are now being studied for cancer treatment. The role of adipotide in cancer research is limited but promising.
Buy FTPP Adipotide Peptide vial [size]
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FTPP Adipotide Specifications
Molecular Formula: C152H252N44O42
Molecular Weight: 2611.41 g/mol
Physical Appearance: White Lyophilised Solid
Form: Sterile Filtered White Lyophilized
Solubility: Water Soluble
Storage: Peptides should be refrigerated at 4˚C or below for a period of up to 3 months. To prolong the life span of the peptides they may be placed in a freezer for up to 12 months. Once reconstituted peptides should be refrigerated/stored at 4˚C for up to 30 days.
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