HGH Fragment 176-191 CJC-1295 DAC Pre-Mixed Pen 2.5mg

Description

HGH Fragment 176-191 CJC-1295 DAC Pre-Mixed Pen 2.5mg

HGH Fragment 176-191 CJC-1295 DAC Pre-Mixed Pen research peptide has been shown in animal studies to aid in weight loss whilst strengthening muscles and bones.

HGH Fragment 176-191 is a synthetic fragment of human growth hormone derived from the natural hormone (hGH). Known for its capacity to speed up fat loss, it’s sometimes called the “lipolytic fragment”. Laboratory research found other effects such as blood sugar levels are reduced, cartilage is repaired, and insulin sensitivity is not altered due to its use.

CJC-1295 is a short peptide analogue of GHRH. When CJC-1295 was first created in the 1980s, it was found to boost muscle regeneration and growth, speed up wound healing and strengthening bones, and increase fat burning. In addition, blood sugar control and the immune system may also benefit from it.

Specifications

HGH Fragment 176-191 CJC-1295 DAC Pre-Mixed Blend contains the following:

HGH Fragment 176-191 

Molecular Formula: C78H125N23O23S2
Sequence: Tyr-Leu-Arg-IIe-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe
Molecular Weight: 1817.12 g/mol

CJC-1295 DAC 

Molecular Formula: C152H252N44O42
Sequence: H-Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-NH2
Molecular Weight: 3367.9 g/mol

Size: 1 Single mixed cartridge | 2 Pre mixed cartridges | 3 Pre mixed cartridges | Pen kit with 1 pre mixed cartridge

Research

CJC-1295, a robust GHRH analogue, has effects beyond increasing GH release. For example, in a clinical trial the peptide has been demonstrated to aid intestinal inflammation, cardiac function, and wound healing in animal experiments [1] [2]

With fragment 176-191, it is possible to increase focused fat burning, which CJC-1295 can only do to a limited extent. However, in laboratory research, it has been demonstrated to be an essential inducer of adipocyte catabolism (body fat reduction) [3].

The peptide is called the “lipolytic fragment” because it is far more effective than most GHRH agonists in increasing fat metabolism [4]. Adding fragment 176-191 to the mix can increase fat burning, especially when paired with increased GH release, and alter metabolism to favour lean body mass accumulation [5].

In animal models, the hGH sequence fragment 176-191 has been shown to increase fat burning and alter metabolism toward lean muscle mass maintenance. It also lacks several of the negative consequences of hGH, such as insulin resistance, long-bone growth, and oedema.

The current investigation suggests that the fragment may help regulate GH secretion by influencing typical physiologic pathways. CJC-1295, a synthesized growth hormone-releasing hormone, may counteract the effects of fragment 176-191. CJC-1295 raises GH basal, peak, and free plasma levels.

Only free HGH is biologically active. So CJC-1295 can compensate for a physiological reaction to 176-191. These advantages would be acquired without affecting normal growth hormone output.

References:

[1] https://pubmed.ncbi.nlm.nih.gov/ 11445245/

[2] https://pubmed.ncbi.nlm.nih.gov/ 31070727/

[3] https://pubmed.ncbi.nlm.nih.gov/ 11713213/

[4] https://pubmed.ncbi.nlm.nih.gov/ 11673763/

[5] https://pubmed.ncbi.nlm.nih.gov/ 11146367/

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