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Humanin Pre-Mixed Pen 10mg

Humanin is a small mitochondrial-derived peptide that has gained attention for its potential anti-aging and neuroprotective properties. It has been shown to inhibit cell death and protect against oxidative stress, making it a promising candidate for therapeutic interventions in age-related diseases.

Pen Kit & Pre-Mixed Cartridge contains:

1 x Pre-Mixed Cartridge (The cartridge is pre mixed with the peptide vial of your choice and Bacteriostatic Water)
1 x Peptide Cartridge Pen
3 x Pen Needle Tips
1 x Pen Carry Case

Please note: Single 1, 2 & 3 Pre-mixed Cartridges do not come with a Pen Kit

£51.49£149.47

SKU PLG: Humanin Pen Categories ,

Description

Humanin Pre-Mixed Pen 10mg

Research has demonstrated that the naturally occurring polypeptide humanin (HN) reduces the death of neurons caused by several genes linked to Alzheimer’s disease. Encoded by mitochondrial DNA, the Humanin peptide functions as a cytoprotective protein, keeping cells from undergoing apoptosis.

Cell death that has been programmed is called apoptosis. The experiments show that it protects the cells from this harmful process, which maintains their health. In addition, it shields the retina of the eye, muscle cells, heart tissue, and neurons.


Specifications

Sequence: Met-Ala-Pro-Arg-Gly-Phe-Ser-Cys-Leu-Leu-Leu-Leu-Thr-Ser-Glu-Ile-Asp-Leu-Pro-Val-Lys-Arg-Arg-Ala
Molecular Formula: C121H205F3N34O34S2

Size: 1 Single mixed cartridge | 2 Pre mixed cartridges | 3 Pre mixed cartridges | Pen kit with 1 pre mixed cartridge


Humanin Research

Although research on the benefits of humanin is limited due to it being a relatively new pepide, there is enough evidence to suggest the following benefits of this peptide:

Anti Aging Properties

Research by indicates that growth hormone (GH) depletes Humanin peptide levels. In one study, researchers discovered that mice with inadequate GH production had higher levels of HN and lived longer than mice with adequate GH production [1].

Furthermore, it has been demonstrated that high-dose nitric oxide (HN) inhibits cell death, enhances insulin sensitivity, lowers inflammation, stops cell death, and dissolves atherosclerotic plaques. Taking a humanin supplement may help prolong life, according to the results of recent studies [2].

Neuroprotection

Rat studies suggest that humanin may provide protection against programmed cell death under certain conditions. The peptide, according to the researchers, can prevent cell death brought on by the accumulation of beta-amyloid plaque, hence protecting neurons in the situation of Alzheimer’s disease. In high-intensity NMDA pulse experiments, the antioxidant humanin 10mg pre-mixed pen has also been demonstrated to guard against excitotoxic cell death [3].

Scientists think that humanin function could soon be a practical therapy option for neurodegenerative disorders like Alzheimer’s disease and other types of dementia with more thorough research.

Neurons are protected by humanin 10mg pre-mixed pen in two different methods, according to clinical studies. By using these two strategies, mitochondria are unable to initiate the death process. The Bcl-2 boosting proteins tBid and Bid are inhibited by humanin, which stops them from initiating the apoptotic signalling cascade.

Scientists in Argentina have found that astrocytes secrete the neuroprotective protein humanin to shield hippocampal synapses from damage. It has been shown that supplementing older animals with humanin can significantly reduce age-related deficits including memory loss [4].

Diabetes

In addition to these benefits, studies have demonstrated that HN can reduce pancreatic beta-cell mortality and enhance glucose metabolism in animals without diabetes. This implies that humanin might be useful in the treatment of diabetes, both type 1 and type 2.

According to lab research, humanin also acts on the hypothalamus, increasing the liver’s sensitivity to insulin and assisting in the maintenance of a healthy blood glucose level.

Therefore, it has been shown in recent studies that humanin can treat obesity by preventing weight gain by raising the release of insulin in response to glucose stimulation [5].

Heart disease

According to research, the humanin peptide helps defend blood arteries against the repercussions of bad cholesterol, commonly known as oxidised LDL cholesterol, by lowering inflammation. The amount of species in the blood is halved as a result of the interaction between LDL oxidation and the generation of free radicals. It is significant because it reduces cell death by half.

Humanin levels must stay consistent in order to maintain your health because they decrease with ageing. Furthermore, a recent study suggests that the peptide humanin has potential applications as a cardiovascular disease treatment and diagnostic marker.

Humanin can also help prevent damage caused by left coronary occlusion by increasing the activity of AMPK and eNOS in the body, hence lowering oxidative stress levels in the bloodstream [6].

Bone Health

Humanin pre-mixed pen may help bones in two ways, according to research. The first is to prevent chondrocytes—the cells that keep bones strong—from dying. Humanin inhibits the production of osteoclasts and stimulates the growth of chondrocytes. The cells that break down and rebuild bone are called osteoclasts. When hyperactive, it results in significant loss of bone. By preventing this development, Humanin pre-mixed pen 10mg supplements can significantly reduce bone growth and loss [7].

Eyes

A study (AMD) found that humanin protects the RPE. From a therapeutic standpoint, this is one of the most significant advantages for human health that is offered.

The retina’s vision-producing cells are fed by the RPE. It also preserves the health of the inner eye, filters blood components, and absorbs light.

By boosting mitochondrial levels and guarding against oxidative stress and RPE cell death, humanin prevents AMD.

RPE function is said to be improved by supplementing with humanin. However, further studies on mice are needed for retinal illnesses like AMD [8].

Summary

Humanin pre-mixed pen 10mg binds to extracellular or intracellular receptors to produce neuroprotective and cytoprotective effects. Furthermore, it has been shown that Humanin decreases insulin resistance, lengthens life, and prevents cellular death.

Due to the peptide’s recent discovery, clinical investigations are still awaiting even though Humanin pre-mixed pen 10mg peptide has demonstrated encouraging results in research. Thus, in order to fully characterise the profile of this peptide and ascertain its potential as a therapeutic agent for prevalent neuro illnesses, clinical trials are currently being conducted.

References

[1] https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC4255622/

[2] https://gero.usc.edu/2020/06/ 24/protein-in-mitochondria-may-regulate-health-and-longevity/

[3] https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC6256269/

[4] https://faseb.onlinelibrary.wiley. com/doi/10.1096/fj.02-0018fje

[5] https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC3705736/

[6] https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC3774506/

[7] https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC6717796/

[8] https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC7263384/

Buy Humanin Pre-Mixed Pen 10mg

Pharma Lab Global is one of the best locations to purchase high purity Humanin Pre-mixed Pen for research use. Pharma Lab Global is a trusted supplier of peptides worldwide. You have the option to buy Humanin Peptide Vial and Humanin Nasal Spray from here. Buy Humanin Peptide from Pharma Lab Global today!


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DISCLAIMER: All products sold by Pharma Lab Global are for research and laboratory use only. These products are not designed for use or consumption by humans or animals. They are not to be classified as a drug, food, cosmetic, or medicinal product and must not be mislabelled or used as such. By purchasing from our Website the buyer accepts and acknowledges the risks involved with handling of these products. All articles and product information provided on this Website are for informational and educational purposes only. Handling and use of these products should be restricted to suitably qualified professionals.

Additional information

Cartridge

1 Single mixed cartridge, 2 Pre mixed cartridges, 3 Pre mixed cartridges, Pen kit with 1 pre mixed cartridge

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