Description
KPV Pre-Mixed Pen 2mg
In wound healing investigations, KPV Pre-mixed peptide and other Alpha-MSH derivatives have been associated to improved wound healing, infection reduction, inflammation reduction, and better cosmetic outcomes. So, when it comes to scar reduction after surgery, KPV and comparable peptides could become indispensable.
KPV pre-mixed pen 2mg contains an alpha-melanocyte-stimulating hormone C-terminal peptide fragment (alpha-MSH). Short alpha-MSH derivatives have been examined to compare their effectiveness against ischemia, sexual effects, photoprotection, energy homeostasis, and eating behaviour.
Lysine-proline-valine (KPV), a mixture of these three amino acids, is a potent anti-inflammatory agent. KPV is being investigated as a possible treatment for inflammatory bowel disease. As previously stated, anti-inflammatory properties have been observed in the gastrointestinal tract, central nervous system, circulatory system, lungs, and joints.
Specifications
Sequence: Lys-Pro-Val
Molecular Formula: C16H3oN4O4
Molecular Weight: 342.43 g/mol
Size:Â 1 Single mixed cartridge | 2 Pre mixed cartridges | 3 Pre mixed cartridges | Pen kit with 1 pre mixed cartridge
Research
Gut Health
The most effective way to reduce intestinal inflammation is using KPV pre-mixed pen 2mg. In mice with inflammatory bowel disease (IBD), this drug reduces inflammatory infiltrates, MPO activity, and overall histological indications of inflammation. This peptide accelerated recuperation and raised body weight in mice. The distribution of this C-terminal peptide fragment (alpha-MSH) via nanoparticles functionalized with hyaluronic acid aids in directing the virus’s inflammatory capabilities to specific intestinal regions. Inhibiting TNF-alpha reduces inflammation and enhances mouse mucosa healing.
According to investigations, the peptide inhibits both NF-kappaB and mitogen-activated protein kinase (MAPK). TNF-alpha, NF-kappaB, and MAPK inhibitors reduce intestinal inflammation. Mice treated with KPV have shorter colons and lower colonic infiltration than control mice [1].
Anti-inflammatory
The peptide promotes inflammation without the pigmentation often associated with normal scar formation. In addition, KPV pre-mixed pen 2mg has anti-inflammatory and antibacterial effects. It inhibits the growth of Candida albicans and Staphylococcus aureus, so preventing burns and other serious wounds from becoming infected. The peptide has an edge over other anti-inflammatory medications that reduce the body’s ability to fight infection [2].
Scarring
KPV pre-mixed pen 2mg can help reduce chronic inflammation, which causes hypertrophic scarring (e.g., keloid). It is caused by widespread macrophage infiltration, TNF immunoreactivity, and neutrophil abundance. In this situation, alpha-MSH reduces scarring and inflammation. These findings indicate that this peptide could be used to prevent scarring produced by some chemotherapy treatments. This strategy would not only reduce the negative side effects of cancer therapies, but it would also make it easier to provide larger doses of these medications to get greater results [3].
Summary
Although research into the potential advantages and applications of KPV pre-mixed pen is ongoing, clinical studies have shown that it can reduce infection, fight inflammation in the intestines, and may offer promise for people suffering from IBD. It has been shown that it can accelerate wound healing and prevent hypertrophic scars from growing without causing skin pigmentation, resulting in improved aesthetic results.
References
[1] https://pubmed.ncbi.nlm.nih.gov/ 18061177/
[2] https://pubmed.ncbi.nlm.nih.gov/ 10670585/
[3] https://pubmed.ncbi.nlm.nih.gov/ 25431356/
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