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LL-37 Nasal Spray

The LL-37 peptide has antibacterial properties. Its antimicrobial effects have been shown to work on gram-positive and gram-negative human infections. AMPs, or antimicrobial peptides, could one day replace antibiotics.

LL-37 15ml Contains 5mg

LL-37 30ml Contains 10mg


SKU PLG: LL-37 nasal Categories ,


LL-37 Nasal Spray

Recent studies by our group have shown that peptide LL-37 nasal spray Cap-18 is an antiseptic agent that can be used to treat fungal infections and bacterial infections. It has proved to be useful against bacterial skin infections, particularly in cases where the disease is resistant to most anti-fungal agents.

In addition, it has also shown promise in fighting against bacterial skin infections due to fungal causes, such as candida albicans. Recently, researchers have been studying the peptide LL-37’s benefits for cathelicidic dermatitis and how this substance can benefit people with this chronic skin disorder.

LL-37 nasal spray can be used to treat cathelicidic dermatitis as this substance has proved effective in reducing the inflammation caused by this condition. This Peptide works by inhibiting the production of proinflammatory cytokines, which is one of the main causes of inflammation that can be attributed to cathelicidic dermatitis. As a result, it helps to eliminate the yeast and bacteria that cause cathelicidic skin disorder, thus relieving the symptoms associated with the condition.


Molecular Formula: C205H340N60O53

Molecular Weight: 4493 g/mol

Sequence: H-Leu-Leu-Gly-Asp-Phe-Phe-Arg-Lys-Ser-Lys-Glu-Lys-Ile-Gly-Lys-Glu-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-Asn-Leu-Val-Pro-Arg-Thr-Glu-Ser-OH

Size: 15ml | 30ml



As an immune system component, LL-37 operates by adhering to and interfering with bacterial lipopolysaccharide (LPS), a critical component of gram-negative bacteria. Additionally, it inhibits the growth of gram-positive bacteria, making it effective against staph infections and other bacterial-related disorders [1].

According to studies on skin infections, normal skin has minimal levels of LL-37, but it rapidly accumulates when pathogens penetrate the body. Additionally, as seen in animal experiments, this peptide functions well with other proteins such as mice beta-defensin 2 to defeat the infection [2].

Tissue repair

LL 37 peptide is antibacterial and controls the balance of pro- and anti-inflammatory chemicals in mice. However, scientists say it’s tough to balance inflammation and tissue recovery.

Because while inflammatory reactions assist the body fight invaders, they can also hinder healing, induce scar tissue formation, and perhaps trigger autoimmune illnesses. Fortunately, LL-37 therapy balances inflammation and healing by affecting macrophages, which cause inflammation when infections penetrate the body [3].

When macrophages recognize pathogens, they alert the rest of the body to defend. Next, the immune system destroys the infections, while macrophages produce new signals to lower inflammation. According to animal studies, LL-37 cathelicidin peptide reverses macrophage activation, turning anti-inflammatory macrophages pro-inflammatory.

LL-37 also inhibits biofilm formation, which can help heal wounds caused by P. aeruginosa and Staph infections. In addition, as shown in animal studies, it can kill bacteria and promote wound healing by interacting with fibroblasts and keratinocytes [2].

Inflammation diseases

LL-37 nasal spray is primarily an antibacterial peptide, but it also helps inflammatory illnesses like lupus, arthritis, and psoriasis. Ll-37 modulates the immune system by decreasing apoptotic keratinocytes, enhancing IL-18 and IFN-alpha generation, modifying neutrophils, and reducing atherosclerotic plaque levels.

The immune system isn’t always affected in the same manner by LL-37/CAP-18. In some circumstances, inactivated T-cells respond to the peptide by increasing their inflammatory activity, while activated T-cells decrease it.

Further research shows that LL 37 Nasal Spray has homeostatic benefits, maintaining immune system regulation and reducing the danger of infection-induced over activity.

Experts believe LL-37 Nasal Spray could help control autoimmune inflammation. They assumed it was the source of the inflammation, but new research shows it may be a therapy for autoimmune illnesses [4].


LL-37 has been shown to help arthritis. The peptide was found in high concentrations in arthritic joints in rats [5]. Because ll 37 lowered inflammation.

Another study on mice found that LL-37 Nasal Spray protects against collagen damage caused by inflammatory arthritis [6]. Direct application of LL-37 to afflicted joints can reduce disease severity. Because LL 37 is abundant in inflamed tissues, scientists assume it has anti-arthritic properties. The peptide also appears to regulate interleukin-32, a molecule linked to arthritis.

There’s additional evidence that toll-like receptor 3 activation exacerbates arthritic symptoms. By binding to TLR4, it can produce anti-inflammatory actions [7].

Lung Disease

LPS has been detected in several species in clinical trials. When inhaled, this chemical stimulates healthy lung tissue. However, it does not treat respiratory diseases like asthma or COPD. The peptide LL-37 nasal spray may help treat toxic dust syndrome [8].

According to research findings on LL-37 nasal spray peptide and lung illness, the peptide enhances epithelial cell proliferation and tissue repair. In addition, drawing pulmonary epithelial cells to the injury site encourages the formation of blood vessels that nourish and maintain the new tissue [9].

Intestinal Cancer

Studies reveal that the LL-37 peptide may help with stomach and intestinal cancers. While the investigation is currently limited, vitamin D exposure has anti-cancer properties.

Vitamin D boosts the anti-cancer action of intestinal cancers via LL37 [10].


LL-37 nasal spray is a health-promoting peptide. It induces beneficial reactions in numerous cells throughout the body, including antibiofilm and antibacterial activities.

ll-37 works differently in humans than in animals. Because human trials are conducted on humans, the results of human trials are not comparable.

In LL 37 reviews, people talk about the peptide’s potential effects on the body of mice, which has been studied.


  1. https://pubmed.ncbi.nlm.nih.gov/15980359/
  2. https://pubmed.ncbi.nlm.nih.gov/15963694/
  3. https://pubmed.ncbi.nlm.nih.gov/24185823/
  4. https://pubmed.ncbi.nlm.nih.gov/30372860/
  5. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4137957/
  6. https://pubmed.ncbi.nlm.nih.gov/24091294/
  7. https://pubmed.ncbi.nlm.nih.gov/21708001/
  8. https://pubmed.ncbi.nlm.nih.gov/17655171/
  9. https://pubmed.ncbi.nlm.nih.gov/15964896/
  10. https://pubmed.ncbi.nlm.nih.gov/29843147/
Buy LL-37 Nasal Spray 15ml and 30ml

Pharma Lab Global is one of the best locations to purchase high purity LL-37 Nasal Spray for research. Pharma Lab Global is a trusted supplier of peptides and sarms worldwide. You have the option to buy LL-37 Cap-18 Peptide and buy LL-37 Cap-18 Pre Mixed peptide from here. Buy from Pharma Lab Global today!


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Additional information


15ml, 30ml