Melanotan 2 Nasal Spray

Description

Melanotan 2 Nasal Spray

Melanotan 2 nasal spray, also known as MT2, was initially designed to cure skin cancer, but it’s now widely utilized as a tanning peptide (melanogenesis).

Natural occurring alpha-MSH (alpha-melanocyte-stimulating hormone) has been synthesized into MT2, resulting in melanogenesis. The skin’s melanocytes (tanning cells) create melanin throughout this process (pigment). Therefore, one of the hormones contributing to tanning and darkened skin is Melanotan, an analogue of a peptide found in melanocyte stimulating hormone.

Melanotan 2 contains the Bremelanotide metabolite, which increases libido and sexual performance with few side effects. This is mainly due to the hypothalamus’ impact on the user.

Scientific study has suggested that Melanotan 2 could be a successful fat burner. The brain’s repressed hunger receptors are targeted by this peptide to reduce your appetite. However this peptide is largely known for its ability to tan the skin without sun exposure.

Specifications

Molecular Formula: C50H69N15O9
Molecular Weight: 1024.2 g/mol
Sequence: Ac-Nle-Asp(1)-His-D-Phe-Arg-Trp-Lys(1)-NH2

Size: 15ml | 30ml

Research

Tanning

Studies have shown that by using Melanotan 2 nasal spray, researchers can achieve a more bronzed skin pigmentation without the risks of excessive sun exposure, and with few known side effects.

This tanning peptide was first discovered by researchers looking for methods of treating skin cancer. They hypothesised that an animal’s natural pigmentary system could be stimulated to produce a safe and protective tan before UV exposure. Thus reducing the risk of skin damage in animals.

A little UV exposure stimulates melanin production from the skin’s melanocytes. The tanning peptide Melanotan 2 has been shown to be effective on all skin types in animals.

Melanotan II has been shown to promote melanogenesis with minimal adverse effects. Melanogenesis protects the hypodermis, the layer beneath the skin, from harmful UV-B rays. In addition, absorbing all UV-B light prevents penetration into the skin [1].

Fat loss

Clinical studies have shown significant effects of Melanotan 2 nasal spray on weight loss. In animal models, MT-2 appears to lower fat storage and  decreased appetite. Food preferences and intake are influenced by the MC-4R (melanocortin-4 receptor). Melanotan 2 nasal spray reduces food intake in mice but also alters their liking for fatty foods, according to scientific research.

MT-2 makes mice reject fatty foods they would otherwise enjoy. Similarly, mice lacking the MC-4R receptor eat primarily fat and are unaffected by MT-2. Leptin, which lessens cravings and food intake, has similar effects to MT-2. However, leptin has never been effective in treating obesity, even in individuals that have insufficient leptin [2].

Studies found that MT2 reduces appetite by making the animal consume less, reduces visceral and subcutaneous fat, and increases metabolism and activity, all of which cause weight loss in the animal body [3].

Sexual dysfunction

Most men in the general population can treat erectile dysfunction (ED) with Viagra and other medications that improve blood flow by lowering vascular resistance normally with few adverse side effects. However, not all ED is caused by vascular issues, and therefore viagra (sildenafil) and similar are ineffective in a small percentage of men and the vast majority of women.

Due to its effects on the central nervous system, MT-2 appears to have a broader application. Eighty per cent of men who had a failed response to Viagra responded well to Melanotan 2 nasal spray treatment due to its ability to stimulate erections. Melanotan 2 nasal spray has been studied extensively as a treatment for both male and female sexual desire disorders. MT-2 Future Research MT-2 is a well-studied peptide in terms of human behaviour, sexual desire, and impulse control [4].

Impulse control and alcohol

Researchers have discovered that Melanotan 2 nasal spray may influence oxytocin signalling and thus behaviour in ASD. It has been shown that even rats who prefer alcohol drink less water when given Melanotan II. In addition, melanotan-2 works synergistically with naltrexone (boosting efficacy by over sevenfold) to reduce binge-like ethanol intake in mice [5].

In addition to being an effective alcoholism treatment, these findings suggest that Melanotan II taps into an even more fundamental process of craving and desire in mammals. Also, the role of oxytocin in impulsive behaviour may be clarified by this study. It may even help researchers identify craving pathways and better understand human motivation in areas like work and relationships, among other things [6].

Summary

MT-2 is a well-studied peptide regarding human behaviour, sexual desire, and impulse control, with few side effects. Medical researchers are increasingly interested in Melanotan peptides especially in it’s ability in preventing skin cancers, but more evidence is needed to establish the efficacy of this lab made chemical for safety reasons. However, research is very promising as shown in many clinical studies.

References

[1] https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC42605/

[2] https://pubmed.ncbi.nlm.nih.gov/ 26312834/

[3] https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC5572812/

[4] https://pubmed.ncbi.nlm.nih.gov/ 9679884/

[5] https://pubmed.ncbi.nlm.nih.gov/ 26108334/

[6] https://pubmed.ncbi.nlm.nih.gov/ 21167196/

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