Description
MGF Peptide Vial 2mg
According to animal studies, MGF peptide, also known as Mechano-Growth Factor, promotes muscle growth, tissue repair, wound healing, and brain development. MGF C-terminal increases muscle healing and speeds up recovery time after injury. It may help protect tissue from mechanical stressors from resistance training and running.
MGF is a peptide generated from IGF1. It is thought to be essential for early development.
Animal studies have revealed that MGF peptide can promote tissue growth and repair by stimulating muscle stem cells and increasing protein synthesis. This peptide is now being studied as a therapy for animal muscle loss.
Specifications
Molecular Formula: C124H204N42O41S1
Sequence: Tyr-Gln-Pro-Ser-Thr-Asn-Lys-Asn-Thr-Lys-Ser-Gln-Arg-Arg-Lys-Gly-Glu-Arg-Lys-Cys
Molecular Weight: 2971.99 g/mol
Physical Appearance: White Lyophilised Solid
Form: Sterile Filtered White Lyophilized
Solubility: Water Soluble
Storage: -20˚C
Size: 2mg
Research
Muscle growth
MGF (Mechano growth factor) has been shown to improve muscle hypertrophy, size, and repair in animals by activating satellite cells. Three weeks of MGF infusions increased muscle growth by 25% in rats. This peptide may help alleviate muscle wasting illnesses and double the benefits of exercise [1].
Muscle growth improves basal metabolic rates and speeds up weight reduction in animals. Obesity-related medical issues can be helped by increasing lean body mass, as indicated in animal studies.
Furthermore, transferring myogenic precursor cells may assist increase dystrophin expression in certain muscle-wasting illnesses, including Duchenne muscular dystrophy (DMD) [2]. This reduces the severity of the conditions.
While this treatment looks promising, transplant survival rates are low. However, according to new research, C-terminal peptide can boost myogenic precursor cell survival, resulting in increased transplant success in mice [3].
Inflammation and injury repair
Repetitive joint use, injury and inflammatory conditions like arthritis can degrade cartilage. In addition, they say cartilage heals poorly due to the inadequate blood supply and stem cell availability. Mechano growth factor peptide research has solved many of the constraints of cartilage regeneration in animals.
To survive injury and physical stress, chondrocytes need C-terminal MGF, according to research. MGF supplementation enhances cell survival to guard against and repair damage caused by mechanical pressure on the cartilage [4].
As a result of abundant chondrocytes, mechanical stress and pressure produce disc degeneration in animals, caused by programmed cell death [5].
Researchers discovered that this peptide could stop disc degeneration in mice by inhibiting apoptosis (cell death) [6].
Heart health
The peptide protects heart muscle against ischemia in sheep animals of acute myocardial infarction [7]. The Mechano growth factor peptide injection also reduced cardiomyocyte compromise by 35%.
This is significant because there are now just a few therapies that can lower the severity of a heart attack. We do have clot-busting medications, but they can cause life-threatening bleeding. Moreover, animal research shows that MGF reduces the effect of a heart attack while it is occurring [8].
Brain and neuron health
In 2010, scientists discovered Mechano growth factor peptide in the brains of animals, demonstrating its neuroprotective properties. Additional research in mice suggests MGF protein protects neurons in hypoxic brains.
Studies show that Mechano growth factor peptide treatment improves the progressive muscle weakness seen in ALS and slows down the disease’s aetiology – motor neuron degeneration.
Scientists claim that Mechano-growth factor peptide protects neurons better than any other isoform. It can also rebuild brain tissue after ischemia. With more research, MGF peptide may be used to treat motor neuron death [9].
Summary
When IGF merges with Mechano growth factor, it causes muscular hypertrophy and fast muscle regeneration in animals. M G F works by overworking muscles and increasing tissue healing. It also helps activate muscle satellite cells (stem cells).
The IGF-1Eb isoform can preserve neurons, reduce muscle wasting, and increase animal muscle regeneration.
This peptide’s efficacy has been proven in rat studies. Rats produced significant levels of MGF after muscle damage, promoting skeletal muscle cell proliferation. While research is limited, MGF treatment is promising for muscle loss and tissue injury.
References
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2840678/
- https://pubmed.ncbi.nlm.nih.gov/17845560/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1725070/pdf/v039p00787.pdf
- https://pubmed.ncbi.nlm.nih.gov/29470961/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438874/
- https://pubmed.ncbi.nlm.nih.gov/30858307/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720995/
- https://pubmed.ncbi.nlm.nih.gov/17581790/
- https://pubmed.ncbi.nlm.nih.gov/16144956/
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