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Mots-c Peptide Nasal Spray

The primary goal of this peptide in its synthetic or natural form is to promote increased growth hormone secretion by inhibiting the action of the enzyme that metabolizes insulin and glucose into glycogen.

15ml Nasal Spray contains 10mg Mots-C Peptide

30ml Nasal Spray contains 20mg Mots-C Peptide

£39.41£73.81

SKU PLG: Mots-C nasal Categories ,

Description

Mots-c Peptide Nasal Spray

MOTS-c peptide nasal spray is a mitochondrial-derived peptide that has been found to maintain metabolic balance, reduce obesity, and prevent diabetes in research using animal models. This short peptide is part of a broader set of MDPs that experts claim is important in mitochondrial signalling and energy management.

Recent research shows numerous MDPs are active in the nucleus. Moreover, many of them penetrate the bloodstream, causing systemic effects. Mots-C peptide’s primary function is to stimulate growth hormone release by blocking the enzyme that converts insulin and glucose to glycogen. The enzyme breaks down glycogen stored in the liver and pancreas. As a result, the body can turn fat into energy more efficiently when this the activity of this enzyme increases.

This suggests that Mots-C Peptide nasal spray speeds up fat metabolism. In addition, because increasing glucose levels assist the body in losing fat and maintaining muscle mass, they also help the body burn fat faster.

In animal studies, the MOTS-c peptide nasal spray is a newly found MDP linked to metabolism, lifespan, exercise capacity, weight management, and illnesses like osteoporosis and diabetes.


Specifications

Molecular Formula: C101H152N28O22S2

Molecular Weight: 2174.64 f/mol

Sequence: Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg

Size: 15ml | 30ml


MOTS-C Research

Diabetes and insulin resistance

According to research from the University of South California, MOTS-C peptide nasal spray can prevent the immune system from damaging insulin-producing pancreatic cells. Thus, it prevented type 1 diabetes in mice in the lab. Diabetes type 1 is a common illness worldwide that attacks the immune system’s insulin-producing cells in the pancreas.

MOTS-c peptide nasal spray seems to assist regulatory T-cells, helping to minimize killer T-cell activation in animal tests [1].

Furthermore, the MOTS c peptide is known to target skeletal muscle. It acts as an AMPK activator, improving insulin sensitivity and glucose absorption in muscle cells without increasing insulin levels [2].

In addition to the USC research, several studies using mice models show the importance of MOTSc in the pathophysiology of insulin sensitivity. The peptide may help qualified professionals monitor pre-diabetic lean mice. They further suggest that MOTS-c changes could indicate insulin sensitivity. While the findings in animal models are encouraging, more clinical trials are required to understand the impacts fully, before this research compound is approved from human use.

Weight loss

Researchers at the Leonard Davis School of Gerontology (USC) revealed MOTS c hormone’s efficiency in preventing weight gain from a high-fat Western diet [3]. The discovery found that it could target muscle tissue and reverse diet-induced insulin resistance in animals models.

Researchers gave MOTS-c injections to obese mice fed a high-fat diet to understand the impacts further.  The study found that mots c regulates sphingolipid, monoacylglycerol, and dicarboxylate metabolism. In addition, Mots c prevented fat formation and weight loss in test animals by downregulating these pathways [4].

The relationship between MOTS-C peptide nasal spray and fat loss has acquired scientific traction. According to a study, a lack of fat oxidation in mitochondria may increase circulating fat, prompting the animal body to increase insulin levels to eliminate fats from the bloodstream. The animal body develops resistance to increasing amounts of insulin, causing significant fat deposition and homeostatic change.

Lifespan

MOTS-c peptide nasal spray appears to promote longevity in animal studies. A study found a notable change in the peptide linked to longevity in animals. When the MOTS-c gene is altered, it causes the lysine protein to lose a glutamate residue at position 14. Scientists have not yet identified how this alteration affects the protein’s function in animals. However, they are confident because glutamate has distinct characteristics from lysine.

The mitochondria are an essential metabolic organelle linked to many age-related illnesses. Mots-c peptides may help extend animal test subjects’ lifespan and improve their general health [5].

Heart Health

Reduced MOTS-c levels have been linked to increased endothelial cell dysfunction in animal subjects undergoing coronary angiography. Endothelial cells regulate plaque formation, blood pressure, and clotting. MOTS-c peptide nasal spray stimulates endothelial cells, improving mice’s endothelium and blood vessel efficiency [6].

MOTS-C isn’t the only mitochondrial-derived peptide that can improve heart health. At least three MDPs appear to protect heart cells from inflammation and stress. Thus, MDP dysregulation may play a critical role in initiating cardiovascular disease [7].

Bone

A study found that MOTS-c therapy allowed older mice to run longer than untreated mice. So treated mice outperformed untreated mice. This shows MOTS c peptide can improve cellular exercise performance.

The mots-c peptide stimulates osteoblasts in the bone of test animals, resulting in the creation of type I collagen. It did so by regulating the TFG-beta SMAD pathways, which help osteoblasts thrive and survive. So, MOTS-C peptide nasal spray promotes osteoblast survival and thus increases overall bone strength.

The peptide increases the development of bone marrow stem cells via the same route as osteoporosis. This boosted osteogenesis (bone production) as a result. Research concluded that MOTS-c protects osteoblasts, enhances their health and longevity, and stimulates their production from stem cells. Increasing research may lead to over-the-counter MOTS c medicine as beneficial prevention and treatment for osteoporosis [8].

Summary

MOTS-C peptide, also known as mitochondrial-derived peptide, offers several benefits for metabolic health and longevity. It promotes fatty acid metabolism in the liver and enhances metabolic flexibility and homeostasis. By regulating mitochondrial energy, MOTS-C helps protect against age-related metabolic disorders, insulin resistance, and cardiovascular impairment.

Research has also found that MOTS-C peptide nasal spray may also improve physical function, insulin sensitivity, and age-related metabolic diseases, including obesity. Additionally, MOTS-C peptide aids in glucose uptake regulation, lipid metabolism control, and enhanced insulin sensitivity. With its potential to increase energy expenditure, enhance fat burning, and suppress appetite, MOTS-C peptide shows promise as a valuable tool for overall health and well-being.

References

[1] https://pubmed.ncbi.nlm.nih. gov/30725119/

[2] https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC6185997/

[3] https://gero.usc.edu/2021/08/12/ mots-c-mitochondria-type-1-diabetes/

[4] https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC6640593/

[5] https://www.sciencedirect.com/ science/article/abs/pii/S089158491 6302507?via%3Dihub

[6] https://pubmed.ncbi.nlm.nih. gov/29242099/

[7] https://pubmed.ncbi.nlm.nih. gov/31185388/

[8] https://pubmed.ncbi.nlm.nih. gov/31081069/

Buy Mots-C Peptide Nasal Spray 15ml and 30ml

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DISCLAIMER: All products sold by PharmaLabGlobal are for in-vitro research and laboratory use only. These products are not designed for use or consumption by humans or animals. Nothing on this Website is intended to diagnose, heal, treat, cure, mitigate or prevent disease. By purchasing from our Website the buyer accepts and acknowledges the risks involved with consumption and handling of these products. All articles and product information provided on this Website are for informational and educational purposes only. All products are to be handled by qualified and properly trained research or laboratory professionals only.

Additional information

Weight 0.01 kg
Dimensions 1 × 1 × 1 cm
Size

15ml, 30ml