Description
PEG-MGF Pre-Mixed Pen 2mg
PEG-MGF (PEGylated Mechano-Growth Factor) is a variant of MGF. Scientific study has shown that it helps lower cholesterol, boost immune function, and accelerate tissue healing.
PEG-MGF is an anabolic peptide that is found in skeletal muscle, bones, tendons, the central nervous system, and cardiac tissue as the body’s stress levels increase. It is a variant of insulin growth factor 1 that has been shown in animal tests to improve endurance and immunity, reduce body fat, and lower cholesterol.
PEG-MGF also boosts immune function, which may hasten wound healing in animal subjects.
Specifications
Molecular Formula: C121H200N42O39
Sequence: peg-Suc-Tyr-Gln-Pro-Pro-Ser-Thr-Asn-Lys-Asn-Thr-Lys-Ser-Gln-Arg-Arg-Lys-Gly-Ser-Thr-Phe-Glu-Glu-Arg-Lys-Cys
Size: 1 Single mixed cartridge | 2 Pre mixed cartridges | 3 Pre mixed cartridges | Pen kit with 1 pre mixed cartridge
PEG-MGF Research
Heart repair
In heart muscle repair studies, the peptide Peg-Mgf stops cardiac muscle cells from dying due to hypoxia (a lack of oxygen). The protein also promotes the recruitment of cardiac stem cells to the injury site, which aids in the regeneration and repair of heart tissues and muscles [1].
When compared to placebo rats, peg mgf animals had higher stem cell progression and reduced cell death. According to the researchers, peg-mgf administration early in cardiac disease may give long-term treatment for patients.
Localised peg mgf treatment may also aid in improving cardiac function following a heart attack. Peptide treatment in rats resulted in minimal circulatory remodelling and better hemodynamics compared to untreated rats [2].
Muscle repair
PEG MGF injection into muscle tissue protects cells by lowering inflammatory hormones and oxidative stress, according to studies in mice models with muscle injury [3].
The peptide peg mgf has been shown in studies to reduce inflammation and speed up healing after exercise-induced muscle tissue injury [4].
According to studies, Pegylated MGF advantages include increased lean body mass, energy, and slowing the ageing process. Furthermore, animal studies have indicated that it can increase fat metabolism and muscle repair, implying that it can improve athletic performance; nevertheless, it is not yet licenced for human use and is only appropriate for research reasons.
PEG MGF-treated mouse model studies revealed a 25% increase in muscle fibre size [5].
Bone repair
A recent study found that the PEG-MGF peptide appeared to speed up bone healing. It induces a rise in the number of osteoblasts, the cells that form new bone.
High dosages of PEG MGF in rabbits resulted in the same level of healing at four weeks as control rabbits at six weeks[6]. Scientific experts seek to discover methods to accelerate bone recovery and shorten the period mice with bone injuries remain immobilised. It would represent a big step towards healing and recovery.
Neuroprotection
A study on neuronal degeneration induced by old age found that high PEG-MGF levels in the brain prevented degeneration. In addition, the peptide boosted cognitive performance in mice. However, the efficacy of the PEG MGF medication varies according to age. The study discovered that pegMGF overexpression early in life had the greatest impact on the mice’s development [7].
Also, PEG MGF therapy improves muscle weakness and lowers motor neuron loss in rats’ brains. In animal experiments, this peptide has been demonstrated to lessen the burden of neurological disorders while improving overall cognitive performance [8].
Summary
PEG-MGF pre-mixed peptide is a synthetic version of Mechano Growth Factor, offers numerous applications and advantages. It has been proven to boost the number of muscle stem cells, which promotes muscle growth and repair through various studies. PEG-MGF may potentially improve nutrient delivery to muscle cells and increase insulin-like growth factor 1, boosting vitality and slowing the ageing process. Furthermore, studies show that supplementing with PEG-MGF can preserve cardiomyocytes after myocardial infarction and aid in tissue regeneration, resulting in speedier recovery and fewer problems. Another distinct advantage is its possible use in dental trauma and operations, enhancing tooth hardness.
References
[1] https://pubmed.ncbi.nlm.nih.gov/ 24908137/
[2] https://pubmed.ncbi.nlm.nih.gov/ 25678113/
[3] https://pubmed.ncbi.nlm.nih.gov/ 31164836/
[4] https://pubmed.ncbi.nlm.nih.gov/ 19567392/
[5] https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC1725070/
[6] https://pubmed.ncbi.nlm.nih.gov/ 21057789/
[7] https://pubmed.ncbi.nlm.nih.gov/ 28683812/
[8] https://pubmed.ncbi.nlm.nih.gov/ 16144956/
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