Thymosin Alpha-1

Description

Thymosin Alpha-1 Peptide Vial 10mg

Thymosin Alpha-1 is a regulator of immune function, which is a naturally found protein. It is currently been studied for infections (e.g. tuberculosis, cytomegalovirus), chronic hepatitis, cystic fibrosis, respiratory disorders, and even cancer. Initially discovered in 1972, Thymosin alpha-1 is a powerful immune function modulator separated from thymus gland tissue.

Thymosin Alpha-1 research suggests it can help boost the immune system cells and fight off diseases. This peptide is very useful in treating infections, it also can prevent infection and boost the immune system to fight the infection effectively.  Thymosin Alpha-1 can accomplish this by working with our body’s T-cells and maturation the killer variation of this cell type in our body.

Lymphocytes are a type of white blood cell in the immune system that produces T-cells. Among them are the B-cells and natural killer cells. The body’s adaptive immune response depends on each of them. For example, when the body attacks pathogens, it stops them from multiplying and spreading throughout the body.

Killer cells and helper cells are the two most common types of various types of cells within the human body. Viruses and foreign cells are both killed by these cells. When suffering from any form of infection, Thymosin Alpha-1 could help reduce the swelling and inflammation, which helps speed up the recovery process. 

Specifications

Molecular Formula: C129H215N33O55
Sequence: Ac-Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-Thr-Lys-Asp-Leu-Lys-Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asn-OH
Molecular Weight: 3108.3 g/mol
Physical Appearance: White Lyophilised Solid
Form: Sterile Filtered White Lyophilised
Solubility: Water Soluble

Size: 10mg

Research

Immunity

Clinical studies have found that Thymosin Alpha-1 helps the body combat infections, diseases, and ailments. Animal studies shows that it induces Z cells to locate and destroy germs, viruses, and tumour cells.

This peptide restores immunological function and eliminates infection in mice without thymus glands. In addition, Thymosin Alpha-1 promotes immune system signalling pathways to boost cytokine production [1].

Studies show that supplementing with Thymosin Alpha-1 can regulate arthritis, lupus, and other inflammation. In addition, recent research reveals peptide Thymosin Alpha-1 can treat breast, lung, colon, and other malignancies [2].

As found in experiments Thymosin Alpha-1 can boost the immune systems of animals, and it may improve the efficacy of vaccines. Due to the risk of administering live germs, many vaccinations contain dead pathogens instead. However, inactivated vaccinations are less effective. In the future, Thymosin Alpha-1 10mg vial vaccination could improve the immune system, preventing illness and disease [3].

Thymosin Alpha-1 could also treat sepsis, a life-threatening illness caused by an overactive immune system. Therefore, the peptide could save lives, prevent organ damage, and prevent long-term consequences by modulating the immune response. Further research is needed, but it looks promising potential as a sepsis therapy and preventative drug [4].

Blood pressure

Recent research reveals Alpha-1 can decrease blood pressure by blocking ACE (angiotensin-converting enzyme). By inhibiting ACE, Thymosin peptide lowers blood pressure, reduces cardiac remodelling, and slows plaque development in animals. In addition, research shows it improves renal function. Animal studies show that Thymosin Alpha-1 has few known adverse effects, unlike many ACE inhibitors [5].

Cystic fibrosis

Inflammation from cystic fibrosis promotes increased infection rates, poor mucus clearance, and other problems. It’s caused by CFTR, an ion channel protein that controls the body’s salt and water balance. Research shows Thymosin Alpha-1 peptide can improve CFTR performance and reduce inflammation. As a result, scientists hope Thymosin Alpha-1 therapy could be at the forefront of future treatment for cystic fibrosis [6].

Fungus

The immune system has a unique cell type that can detect fungal infections, called dendritic cells. Studies show that Thymosin Alpha-1 medications can increase the immune system’s ability to fight animal fungal infections. In animal models of aspergillus infection, this peptide activates T-helper cells. It may improve OTC fungal treatments [7].

Dendritic cells transmit antigens to other immune cells so they can recognise them and respond appropriately. Skin, lungs, nose and GI systems have many dendritic cells. Animal study shows that thymosin alpha 1 helps these immune system’s initial responders work optimally [8].

Cancer Cells

Thymosin Alpha-1 (Tα1) has gained significant attention for its potential impact on cancer treatment due to its immunomodulatory properties. Research indicates that Tα1 can enhance immune capabilities, potentially aiding in treating tumours more effectively. Clinical trials have shown its effectiveness in treating several types of cancer, including lung cancer, colon cancer, melanoma, breast cancer, and non-small cell lung cancer (NSCLC), showing promise in improving overall survival rates.

Furthermore, Tα1 has been explored in combined treatments with low doses of interferon or interleukin, suggesting potential synergy in cancer management. Its ability to modulate the immune system and improve postoperative survival further underscores its potential as an adjunctive treatment in cancer care [9].

Summary

Thymosin Alpha-1 peptide offers a huge list of potential benefits, including its role in controlling inflammation, boosting immunity, and enhancing tolerance. This immunostimulatory peptide shows promise in treating viral infectious diseases such as hepatitis, bolstering immune response, resisting infections, improving vaccine effectiveness, and suppressing tumour growth are just a few of its potential applications. Furthermore, it demonstrates antibacterial and antifungal properties, enhances natural killer cell activity, and plays a crucial part in promoting thymus immune cell production and restoring lymphocytopenia.

References

[1] https://pubmed.ncbi.nlm.nih. gov/27450734/

[2] https://pubmed.ncbi.nlm.nih. gov/20536460/

[3] https://pubmed.ncbi.nlm.nih. gov/29730515/

[4] https://pubmed.ncbi.nlm.nih. gov/30063866/

[5] https://pubmed.ncbi.nlm.nih. gov/30974297/

[6] https://pubmed.ncbi.nlm.nih. gov/28394330/

[7] https://pubmed.ncbi.nlm.nih. gov/14982877/

[8] https://pubmed.ncbi.nlm.nih. gov/17495242/

[9] https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC7747025/

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