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It’s a nootropic and anxiolytic peptide used in treating anxiety and improving learning. It’s a heptapeptide and a synthetic analogue of tuftsin.


SKU PLG: Selank vial Categories ,


Selank Peptide Vial 5mg

Selank has been used as an antidepressant by some people, and has proved to be very effective in treating depression.

It was found that the neuroprotective activity of Selank is very similar to that of the benzodiazepines, and this has the reason that the mechanism of action of these medicines is identical as well. Peptide Selank can reduce the levels of Serotonin in the brain very effectively and therefore it helps in controlling the depression.

Serotonin is a neurotransmitter which is found in the brain and works to regulate various functions in the body. It helps to control multiple chemical reactions in the brain and to make the mind active and to fight off against depression. It is mainly responsible for the regulation of mood and the fight off against the negative feelings like anxiety and depression.
It can even be responsible for the match of aggressive behaviour. Selank is useful in controlling these emotions.


Molecular Formula: C33H57N11O9
Sequence: H-Thr-Lys-Pro-Arg-Pro-Gly-Pro-OH
Molecular Weight: 751.9 g/mol
Physical Appearance: White Lyophilised Solid
Form: Sterile Filtered White Lyophilised
Solubility: Water Soluble

Storage: -19˚C

Size: 5mg



Experts say selank’s clinical effects are similar to benzodiazepines [1]. The peptide can help with anxiety, mood, and stress.

Selank therapy reduced anxiety symptoms in 62 mice in a clinical trial. Anxiety disorder sufferers saw a more significant decrease in symptoms.

It lasted a week after the last selank dosage in another study on anxious mice.

Anxiety levels in mice were also significantly reduced by selank treatment.

Anxiety-reducing drug phenazepam’s side effects like memory loss and fatigue were reduced by selank in a 70-mouse trial.

Both selank and benzodiazepines effectively treat anxiety in rats, but the peptide appears to be more effective than the latter. Researchers believe combining the two treatments work best for treating chronic mild stress [2].

Stress-induced increased enkephalinase activity in the blood of mice with anxiety and stress disorders, according to research on this peptide. Still, because enkephalins have shorter half-lives, they can’t cope or recover. It works by reserving enkephalins, preventing anxiety-inducing degradation [3].


Studies show that anxiety can impair memory. However, animal studies show that anti-anxiety drugs like selank can minimize this effect.

A selank injection improved memory in rats trained with food rewards. Regardless of rat anxiety levels, this protein boosts memory [4].

Selank may modify memory by changing gene expression in the hippocampus, new research suggests. Selank nasal spray altered the mRNA levels of 36 genes in rats. These genes encode plasma membrane proteins that modulate memory and learning. The peptide affects neuron functions to make memory retrieval easier.

This peptide has also been shown to improve memory after brain injury. In addition, scientists believe the inhibition of the catecholamine system is related to the cognitive restoration in rats given neurotoxin and then selank [5].

Researchers hope that this peptide will soon be approved by the FDA to treat cognitive impairment. It could help those with traumatic brain injuries regain memories.


Selank peptide has been shown to suppress the gene that produces IL-6, an inflammatory cytokine, in depressed mice. This effect occurs only in depressed mice, implying that it could treat anxiety-asthenic disorders.

Other treatments like benzodiazepines do not prevent the pain and fatigue associated with anxiety. This peptide has the ability to alter IL6 expression and the breakdown of enkephalins, the body’s natural painkillers.

Selank affects the expression of 34 genes involved in inflammation, including cytokines, receptors, and chemokines. The peptide can also affect BcI6 expression, a gene involved in the immune system, according to animal studies [6].

Selank fragments can temporarily alter gene expression for CAsp1, C3, Xcr1, and ll2rf, affecting the immune system’s balance and reducing inflammation.

This peptide can also induce interferons, which are antiviral molecules and has been shown to protect cells from viral infections.

Overall, these studies show that this peptide strengthens the immune system.

Blood pressure

Selank showed significant blood pressure lowering effects on cats for 2-3 minutes. The peptide also increased brain blood flow by up to 24% for 10 minutes.

Researchers believe that this peptide may have short-term cardiovascular effects. However, it’s too early to tell if these short-term effects are beneficial. More research should reveal more.

Pain relief

This peptide treatment may slow enkephalin degradation by inhibiting blood enzymes that break them down. Enkephalins are natural pain relievers found in abundance in mice’s adrenal glands and brain. Inhibiting the normal stress response by lowering enkephalin levels in the brain [7]


A powerful peptide, selank has numerous health benefits. For example, the nootropic has been shown to treat anxiety disorders and help mice cope better in stressful situations.

The peptide may also improve memory and learning, improve blood flow, boost the immune system, and reduce pain.


  1. https://pubmed.ncbi.nlm.nih.gov/26924987/
  2. https://pubmed.ncbi.nlm.nih.gov/28280289/
  3. https://pubmed.ncbi.nlm.nih.gov/12432865/
  4. https://pubmed.ncbi.nlm.nih.gov/20919548/
  5. https://pubmed.ncbi.nlm.nih.gov/18683497/
  6. https://pubmed.ncbi.nlm.nih.gov/21609736/
  7. https://pubmed.ncbi.nlm.nih.gov/11443939/
Buy Selank Peptide vial 5mg

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Additional information


5mg Vial, Kit = 5mg vial, bac water, syringes