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Melanotan 1 (MT-1) differs from alpha-MSH by a single amino acid and was first created as a sunless tanning agent. However, MT-1 was quickly determined to have a wide range of other effects, including sexual stimulation, increased appetite, changes in baseline metabolism, and changing skin pigmentation. In addition, this peptide and other melanocortin-binding proteins have helped scientists better understand the melanocortin signalling mechanism after subsequent research.
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