Description
ARA-290 Pre-Mixed Pen 2mg
Peptide ARA-290 Pre-Mixed Pen , has been shown in clinical studies to reduce HbAl c and improve cholesterol levels, modulate neuropathic pain, stimulate wound repair, and to provide anti-inflammatory properties.
Specifications
Sequence: ZEQLERALNSS
Molecular Formula: C51H84N16O21
Molecular Weight: 1257.3 g/mol
Size: 1 Single mixed cartridge | 2 Pre mixed cartridges | 3 Pre mixed cartridges | Pen kit with 1 pre mixed cartridge
Research
Protection and Tissue Health
Studies using rodents indicate that by decreasing macrophage activation, ARA290 peptide therapy promotes the health and longevity of islet cells in the body. Islet cells regulate blood sugar, and glucose levels better than exogenous insulin, resulting in fewer problems. Although transplanted islet cells do not tolerate well, research indicates that this peptide can extend their longevity.
Investigations have found that the ARA-290 nasal peptide guards against natural inflammatory reactions and enhances tissue protection. Animal studies have shown that this can result in faster wound healing, repair and lower mortality [1].
Preventing Disease
Mice research has demonstrated that ARA-290 nasal can increase the longevity of cells and helps endothelial colony-forming cells (ECFCs) grow and repair blood vessels. Protecting these cells could prevent retinal ischemia which is the leading cause of blindness in western countries [2].
Furthermore, research has indicated that the ARA290 peptide can increase endothelial cell-derived fibroblasts’ migration, growth, and health (ECFCs), explicitly targeting parts of the vasculature that require repair.
In the medical world, ara290 has the potential to play a significant role in the future of protein synthesis, tissue repair, and hormone production.
Immune System Booster
More recently, clinical research has shown that ARA-290 may aid in an immune system boost. Tissue-protective receptor (TPR) is expressed on various immune cells, including mast cells, lymphocytes, dendritic cells, and macrophages.
Based on these scientific findings, ara-290 pre-mixed pen can bind to this TPR on immune cells and alter their activity directly. When ARA 290 increases TPR, it drastically reduces the release of proinflammatory cytokines like IL-6. This activates the innate immune response to prevent illness, or make the symptoms less severe [3].
Pain Relief
Scientists have also suggested that the select IRR (innate repair receptor) can lower inflammation and relieve neuropathic pain. Animal studies show that injecting ARA-290 can decrease the activity of TRPV1 and the IRR. In addition, further studies have demonstrated that by acting this particular receptor, the ARA 290 peptide can alleviate pain caused by or associated with, but not limited to, multiple sclerosis, diabetes and limb amputation.
Treatment with ARA-290 pre-mixed pen can also increase the number of tiny nerve fibres, which often accompany autoimmune illnesses, causing substantial pain reduction. In addition, as a result of research on animals, professionals are confident that a high dose of ARA-290 nasal could be a successful in treating nerve damage caused by disorders such as diabetes, thyroid disease, celiac disease, and HIV [4].
Summary
ARA-290’s unique process of controlling nerve pain has unsurprisingly gained a lot of attention. In addition, the peptide’s immune-modulating properties, it’s capacity to stimulate the repair of wounds, and potential to protect the vasculature during inflammatory reactions have also gathered a lot interest in the medical world. ARA-290’s ability to regulate neuropathic pain is the main focus of most recent studies.
Currently, the peptide is being tested to treat diabetic neuropathy and sarcoid neuropathy. ARA-290 pre-mixed pen is also being tested in laboratory studies to treat systemic lupus erythematosus, multiple sclerosis, HIV, celiac disease, and other chronic conditions that cause pain. In addition, research has suggested patients with inflammatory bowel disease (IBD) are increasingly interested in using ARA-290 as a potential disease-modifying agent.
References
[1] https://pubmed.ncbi.nlm.nih. gov/24555851/
[2] https://pubmed.ncbi.nlm.nih. gov/30876881/
[3] https://www.sciencedirect.com/ science/article/abs/pii/S0196978 116300031
[4] https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC4365069/
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