CJC-1295 DAC Nasal Spray
Analogues of growth hormone-releasing hormone (GHRH) have been created that retain some properties while removing others. Only the first 29 amino acids of GHRH make up CJC-1295 DAC Nasal Spray . Because it is easier to generate in large numbers than GHRH, this counterpart of GHRH retains GHRH’s physiological properties while being easier to manufacture. hGRF (1-29) was designed to create a more soluble GH secretagogue that retains GHRH’s physiological effects.
CJC-1295 DAC vs. CJC-1295
GHRH analogues such as Sermorelin are modified versions of the first 29 amino acids of GHRH. However, it is not the same as modified GRF (1-29). Also, CJC-1295 was initially manufactured with an extra chemical substance called a drug affinity complex (DAC).
The lysine linker adds DAC to the molecule to protect it while it circulates. It enables CJC-1295 DAC nasal spray to have a longer half-life than GRF by allowing peptides to attach to albumin (1-29)
Molecular Formula: C152H252N44O42
Molecular Weight: 3367.9 g/mol
Size: 15ml | 30ml
Growth Hormone and CJC-1295:
As a GHRH derivative, CJC-1295 stimulates GH release. In an animal study, a single dose of CJC-1295 DAC increased GH levels in mice by 2–10 fold . Results showed that peak GH levels occurred two hours after treatment and lasted six days. Unlike other GHRH derivatives, CJC-1295 DAC preserved normal GH secretion. The results suggest that CJC 1295 is a physiological growth hormone-releasing factor with regular circadian peaks and troughs.
It is crucial to keep GH levels steady and control the maximum amount of GH in the blood to get the most out of the effects without worsening the bad ones. Furthermore, CJC-1295 has been shown to sustain the growth hormone’s physiologic effects on myocardial (heart cell) function and hyperplasia .
CJC-1295 and Growth:
CJC-1295 DAC nasal spray maintains regular GH release in mice lacking normal GHRH physiology . This suggests the peptide is potentially beneficial as a therapeutic for unusual growth in humans and other mammals. In addition, maintaining regular GH pulsatile release ensures the correct release of downstream hormones like insulin-like growth factor-1 (IGF-1).
CJC-1295 and Infertility:
Researchers believe CJC-1295 DAC nasal spray and other GRF equivalents can help infertile women ovulate. Ovulation is known to be affected by IGF-1 and GH release and cycling. In addition, GH and IGF-1 levels rise dramatically around ovulation in animal models of superovulation and humans alike .
In these studies, exogenous GH secretagogues, such as CJC-1295, are also sufficient to induce ovulation. In addition, some investigations suggest that CJC-1295 DAC and its analogues may assist in regulating sperm production in male infertility. However, this last hypothesis has yet to be tested.
Recent scientific studies have shown that CJC-1295 DAC nasal spray helps increase protein synthesis, protein intake, bone density, muscle growth, and a faster recovery time. People who use CJC 1295, whether or not they have DAC, will get the same benefits. That doesn’t mean, however, that DAC doesn’t help with the results, DAC helps to improve the results.
Buy CJC-1295 DAC Nasal Spray
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