CJC-1295 No DAC Pre-Mixed Pen

Description

CJC-1295 No DAC Pre-Mixed Pen

Without DAC, CJC-1295 is a modified GRF (1-29) equivalent (GHRH). To keep all protein properties, the first 29 amino acids of GHRH were altered. As a consequence, the smallest GHRH fragment with complete GHRH properties is CJC-1295 no DAC . CJC-1295 without DAC also has four changed amino chains that limit degradation and oxidation during manufacture, transport, and in vivo while increasing binding affinity to GHRH receptors.

CJC-1295 no DAC, also known as Modified GRF, is a truncated peptide of growth hormone-releasing hormone (GHRH). Clinical investigations have shown that the CJC-1295 no DAC pre-mixed pen, first developed in the 1980s, aids the body’s ability to repair and generate new muscle tissue. It also promotes wound healing, bone strength, and fat burning and metabolism. Furthermore, it may help with blood sugar regulation and the immune system.

Specifications

Molecular Formula: C152H252N44O42
Sequence: H-Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-NH2
Molecular Weight: 3367.9 g/mol

Size: 1 Single mixed cartridge | 2 Pre mixed cartridges | 3 Pre mixed cartridges | Pen kit with 1 pre mixed cartridge

Research

CJC-1295 There is no DAC. GHRH’s behaviours are imitated by the Pre-Mixed Pen. These include muscular hypertrophy, bone growth, wound healing, fat burning, and metabolic speed. It also boosts the immune system and controls blood sugar levels. The Intestine and GRF Early study suggested that GH could aid in the treatment of Crohn’s disease, irritable bowl syndrome, and other inflammatory bowel illnesses. However, the disadvantages of long-term exogenous GH therapy outweigh the benefits.

Gastrointestinal 

Researchers investigated GHRH analogues in search of comparable results without the significant negative effects. CJC-1295 without DAC interacts with VIP receptors and improves gastrointestinal motility in monkeys, according to research [1]. VIPC1, which is found in the gastrointestinal, reproductive, and urinary systems, also appears to interact with this peptide. Improving intestinal motility is crucial in inflammatory bowel disease with constipation [2] [3]. There are now no medications available to treat these illnesses, which cause significant morbidity.

Cardiovascular Benefits

Following a cardiac attack, CJC-1295 No DAC Pre-mixed pens and other GHRH derivatives appear to improve the ability of the heart to pump blood. This could considerably improve the quality of life and minimise mortality in people with heart failure [4]. Furthermore, this discovery has the potential to be used to treat a variety of congenital cardiac disorders, heart failure, pulmonary hypertension, and heart attacks.

Thyroid

Thyroid problems are usually associated with GH release. To investigate this link, hypothyroidism patients were administered CJC-1295 without DAC for this trial [5]. The researchers discovered a link between thyroid hormone and GH and discovered that individuals given T4 had larger GRF reactions. Changing GRF, for example, can help scientists understand human physiology in a variety of ways [6].

Summary

CJC-1295 There is no DAC. There are several advantages to using a pre-mixed pen. For example, animal study has showed that this peptide stimulates natural growth hormone production, promotes fat loss, increases muscular mass, and improves overall health.

References

[1] https://pubmed.ncbi.nlm.nih.gov/ 11445245/

[2] https://pubmed.ncbi.nlm.nih.gov/ 2859987/

[3] https://pubmed.ncbi.nlm.nih.gov/ 12388623/

[4] https://pubmed.ncbi.nlm.nih.gov/ 31070727/

[5] https://pubmed.ncbi.nlm.nih.gov/ 3098458/

[6] https://pubmed.ncbi.nlm.nih.gov/ 2871123/

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