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KPV Peptide Vial

KPV peptide is a potent anti-inflammatory tripeptide composed of lysine (K), proline (P), and valine (V). It has shown promise in the treatment of various conditions, particularly inflammatory bowel disease (IBD). Research suggests that KPV can attenuate inflammatory responses in colonic cells and may have potential therapeutic benefits in reducing inflammation and promoting immune modulation.


SKU PLG: KPV vial Categories , Tag


KPV Peptide Vial 2mg

Alpha-MSH derivatives including KPV have also been linked to improved wound healing, infection reduction, inflammation reduction, and improved cosmetic outcomes in studies. So when it comes to scar reduction following surgery, KPV and similar peptides could become a staple.

KPV is an alpha-melanocyte-stimulating hormone’s C-terminal peptide fragment (alpha-MSH). Many short alpha-MSH derivatives have been studied to identify if they possess the same activity against ischemia, sexual effects, photoprotective properties, or energy homeostasis and benefits on feeding behaviour as alpha-MSH.

Lysine-proline-valine (KPV), a combination of these three amino acids, has the powerful ability to reduce inflammation. KPV is being researched as a potential therapy for inflammatory bowel disease. As mentioned above, anti-inflammatory characteristics have been indicated in the gastrointestinal tract, central nervous system, vascular system, lungs and joints of the organs.


Sequence: Lys-Pro-Val

Molecular Formula: C16H3oN4O4

Molecular Weight: 342.43 g/mol

Size: 2mg

KPV Research


In decreasing intestinal inflammation, KPV is the most important. In mice models of inflammatory bowel disease (IBD), this compound lower inflammatory infiltrates, MPO activity, and overall histological signs of inflammation. This peptide improved the rate of recovery and increased body weight in mice. The delivery of this C-terminal peptide fragment (alpha-MSH) using nanoparticles functionalized with hyaluronic acid assists in directing the virus’s inflammatory properties to specific intestinal sites. Thus, inhibiting TNF-alpha lowers inflammation and promotes the repair of the mouse mucosa.

NF-kappaB and mitogen-activated protein kinase (MAPK) are likewise inhibited by the peptide, according to studies. Inhibition of TNF-alpha, NF-kappaB, and MAPK ameliorates intestinal inflammatory alterations. Compared to control mice, mouse models with the peptide have shorter colons and less colonic infiltration [1].


Clinical studies using animal models have found that this peptide causes anti-inflammatory effects without the pigmentation generally associated with natural scar development. In addition, KPV contains anti-inflammatory and antimicrobial properties. It stops the growth of Candida albicans and Staphylococcus aureus and helps keep burns and other serious wounds from getting infected. The advantage of the peptide is in comparison to other anti-inflammatory medicines, which hinder the body’s capacity to fight infection [2].


This peptide can reduce chronic inflammation, which is responsible for hypertrophic scarring (e.g., keloid). It is brought on by extensive macrophage infiltration, TNF immunoreactivity, and neutrophil abundance. Using alpha-MSH in this context results in improved wound healing and less severe scarring. These results suggest that this peptide could be used to prevent the scarring caused by some chemotherapeutic drugs. This method would not only lessen the bad side effects of cancer treatments but also make it easier to use higher quantities of these medications to get better results [3].


Although clinical research is continuing into the potential benefits and applications of KPV, healthcare professionals have found through research that it can reduce infection, fight inflammation in the intestines and may hold promise for those suffering with IBD. It has also demonstrated that it can accelerate wound healing and stop hypertrophic scars from forming without resulting in skin pigmentation with better cosmetic results.


[1] https://pubmed.ncbi.nlm.nih.gov/ 18061177/

[2] https://pubmed.ncbi.nlm.nih.gov/ 10670585/

[3] https://pubmed.ncbi.nlm.nih.gov/ 25431356/

Buy KPV Peptide Vial 2mg

Pharma Lab Global is one of the best locations to purchase high purity peptides for research use. Pharma Lab Global is a trusted supplier of peptides and sarms worldwide. You have the option to buy KPV Nasal Spray and KPV Pre-Mixed Pen. Buy KPV Peptide from Pharma Lab Global today!


DISCLAIMER: All products sold by Pharma Lab Global are for research and laboratory use only. These products are not designed for use or consumption by humans or animals. They are not to be classified as a drug, food, cosmetic, or medicinal product and must not be mislabelled or used as such. By purchasing from our Website the buyer accepts and acknowledges the risks involved with handling of these products. All articles and product information provided on this Website are for informational and educational purposes only. Handling and use of these products should be restricted to suitably qualified professionals.

Additional information


2mg Vial, Kit = 2mg vial, bac water, syringes