Description
FTPP Adipotide Pre-mixed Pen 2mg
Adipotide, also known as FTPP, is an experimental weight-loss medication that targets the blood supply to fat cells.
A new medication called adipotide has showed great promise in the study of obesity. Tests on FTPP Adipotide Pre-Mixed Pen 2mg , which was first created to treat cancer, have indicated that it may be a useful tool for losing weight.
Adipotide, sometimes referred to as pro-apoptotic peptide or FTPP, kills fat cells by severing their blood supply. The ability of FTPP Adipotide Pre-Mixed Pen to discriminate between blood vessels in the body and blood vessels in fat cells makes it selective. Adipotide not only aids in weight loss but also enhances insulin sensitivity and lessens the effects of type 2 diabetes in monkeys studies.
Specifications
Molecular Formula: C152H252N44O42
Sequence: H-Cys-Lys-Gly-Gly-Arg-Ala-Lys-Asp-Cys-Gly-Gly-Asp-(Lys-Leu-Ala-Lys-Leu-Ala-Lys)2
Molecular Weight: 2611.41 g/mol
Size: 1 Single mixed cartridge | 2 Pre mixed cartridges | 3 Pre mixed cartridges | Pen kit with 1 pre mixed cartridge
Research
Fat loss
Phase 1 clinical trials of adipotide 2011 saw the start of an experiment to evaluate the drug’s capacity to destroy fat cells. Rhesus monkeys were utilised by the researchers to test this notion. They found that apoptosis in WAT blood vessels (white adipose tissue) was induced by feeding animals adipotide.
The lack of blood flow caused fat cells to die as a result, which improved insulin resistance, lowered BMI, and caused fast weight reduction. The adipotide drug also resulted in better eating habits and weight loss. Compared to untreated monkeys, adipotecine-treated monkeys consumed less food [1].
Through the protein receptor prohibitin, FTPP Adipotide may be administered to blood vessels in fat cells. Only two types of cells—white fat and cancer cells—contain prohibitin. Additionally, this protein interacts with adipotide. If prohibitin is exclusively present in cancer tissue and fat vasculature, it would then need to pinpoint a fat-specific target for therapeutic and investigative uses [2].
Cancer research
Prohibitin, the target molecule of adipotecine, has been associated with cancer [3]. A plentiful blood supply is necessary for cancer cells to proliferate and spread. By focusing on prohibitin in cancer cells, advanced cancer treatments that don’t damage neighbouring tissues may be made possible.
Insulin resistance
High blood sugar levels are referred to as glucose tolerance. Blood tests are employed to identify and validate the issue. Consuming a certain amount of sugar and then monitoring blood sugar levels are the steps in a glucose tolerance test. Greater glucose tolerance is indicative of diabetes, and glucose tolerance itself serves as a stand-in for diabetes.
Blood sugar levels can be lowered by exercise and diet, but both need work and dedication. It takes time for them to take effect. Type 2 diabetes is typically caused by uncontrolled hyperglycemia, necessitating the use of insulin and metformin medicines. A peptide called adipotide rapidly increases glucose tolerance without causing weight gain.
Furthermore, and this is very important, the FTPP Adipotide pre-mixed pen lowers glucose tolerance without changing weight. In other words, fat has to be lost, not weight. These findings contribute to our understanding of how diabetes arises and open the door to new diabetic therapies.
There is disagreement over whether adipotecin actually causes fat loss, or if it only lowers food intake, which has the effect of indirectly causing fat loss. Adipotide is most likely directly in charge of the lowering of fat. This idea is supported by the peptide’s effect on glucose tolerance that is unaffected by changes in fat cell density [4].
Summary
The main uses of ciprofexid for research include diabetes and weight loss. The protein kills fat-supplying blood vessel cells as well as the fat cells they supply by selectively targeting these cells. FTPP Adipotide pre-mixed pen is an anti-angiogenic peptide that acts on blood vessels. Cancer treatment with anti-angiogenic agents is now under investigation. Adipotide’s contribution to cancer research is modest yet encouraging.
References
[1] https://pubmed.ncbi.nlm.nih.gov/ 22072637/
[2] https://pubmed.ncbi.nlm.nih.gov/ 15133506/
[3] https://pubmed.ncbi.nlm.nih.gov/ 22049339/
[4] https://pubmed.ncbi.nlm.nih.gov/ 22733798/
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