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AICA Ribonucleotide Peptide Vial 50mg

AICAR (5-aminoimidazole-4-carboxamide-1-β-D-ribofuranoside) is a peptide that occurs naturally in the body and stimulates AMP-activated protein kinase (AMPK) activity. It is commonly used as a pharmacological modulator to enhance AMPK activity and plays a role in energy homeostasis and metabolic pathways. Research suggests that AICAR may have potential benefits in improving glucose tolerance, lipid profiles, and overall metabolic function.


SKU PLG: AICA Vial Categories ,


AICA Ribonucleotide Peptide Vial 50mg

AICA ribonucleotide (also known as AICAR) is adenosine monophosphate’s analogue, and is considered an ampk activator (amp activated protein kinase). It has been used to prevent myocardial ischemia after heart attacks. In addition, AICA ribonucleotide is an antioxidant that may help halt the ageing process. Diabetes, auto-immune disorders, and other inflammatory ailments are being studied with AICAR.


Molecular Formula: C9H15N4O8P
Molecular Weight: 338.21 g/mol
Sequence: 5-amino-4-imidazole carboxamide ribotide
aminoimidazole carboxamide ribonucleotide

Physical Appearance: White Lyophilised Solid
Form: Sterile Filtered White Lyophilized
Solubility: Water Soluble

Size: 50mg


Muscle growth

Muscle fibres are the basic skeletal muscle unit. Muscle fibre types affect meat quality. Therefore, AMPK protein activity was measured in gastrocnemius (GS) muscle fibre composition, enzyme activity, and muscle fibre type-related genes mRNA expression [1].

AICAR increases muscle mass in the body, among other benefits. It is essential for both muscle growth and mass muscle preservation. Testing shows it can also slow down muscle loss.

According to research, AICAR medicine could be used to treat muscle wasting illnesses in the future. In addition, AICAR’s muscle growth outcomes improve with rigorous exercise.

Anti-inflammatory properties

Recent research suggests AICAR is involved in cellular inflammation. AICAR is related to metformin, a long-used diabetic treatment beneficial partly due to its anti-inflammatory actions.

AICAR protects against inflammatory diseases such as asthma, hepatitis, colitis, and atherosclerosis. ACIA ribonucleotide has been shown in studies on mice to reduce inflammation in colitis [2].

AICAR may also help reduce the symptoms of autoimmune disorders and other inflammatory ailments.


AICAR, an amp activated protein kinase commonly abbreviated as AMPK, has been shown to improve sperm motility, fertilizing potential, and metabolism in studies conducted on goats, cats, and chickens, among other species [3] [4].

Heart disease

Inflammation is a frequent cause of cardiovascular disease (CVD). Research on animals has demonstrated that the anti-inflammatory effects of AICAR are so powerful that it can help slow the progression of vascular disorders [5].

The researchers wanted to see what would happen if they gave AICAR to murine models of atherosclerosis and observed the results [6]. The findings revealed that AICAR inhibited the growth of vascular smooth muscle, resulting in a reduction in both short- and long-term problems associated with stent implantation and placement.

According to the findings of the research, activation of AICA ribonucleotide appears to suppress immunological responses that are associated with atherosclerosis. Furthermore, bad cholesterol (LDL) builds up in the bloodstream, causing macrophage proliferation, ultimately resulting in a heart attack. The use of AICAR can help prevent the spread of heart disease and heart attacks and potentially lower their incidence.

Insulin sensitivity

Extensive research on rats shows that high and low AICAR doses reduce inflammation in adipose tissue, which stores energy as fat [7].

Insulin resistance is linked to adipose tissue inflammation. Improved glucose homeostasis happens via decreasing inflammation. For instance, AICA ribonucleotide regulates inflammation in adipose tissue via SIRT1 and macrophages.

Body weight loss and improved insulin resistance were seen in obese animal models.

AICA ribonucleotide research shows that both healthy and diabetic rats have decreased inflammatory responses. There is evidence that AICAR can help increase insulin sensitivity and reduce inflammatory symptoms.


AICA ribonucleotide is an essential protein in metabolic pathways and energy balance that also controls insulin receptors and improves insulin sensitivity in muscle cells. Studies show that AICAR peptide hormone can play an important role in fighting cancer and preserving the heart. It also prevents early blood coagulation. So scientists want to keep studying this protein. Historically, doctors utilized AICAR to keep the heart’s blood flowing. However, the peptide AICA ribonucleotide also shows potential as a diabetes therapy due to its ability to boost tissue metabolism. It does so by altering the body’s muscle composition.


[1] https://www.tandfonline.com/ doi/full/10.1080/09712119.2021. 1889563

[2] https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC4398665/

[3] https://pubmed.ncbi.nlm.nih. gov/31079268/

[4] https://www.frontiersin.org/ articles/10.3389/fcell.2017.00025/ full

[5] https://www.frontiersin.org/ articles/10.3389/fphar.2021. 738420/full

[6] https://www.sciencedirect.com/ science/article/pii/S00222828 13002277

[7] https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC2692788/

Buy AICA Ribonucleotide Peptide vial 50mg

Pharma Lab Global is one of the best locations to purchase high purity AICA Ribonucleotide for research use. Pharma Lab Global is a trusted supplier of peptides and sarms worldwide. You have the option to buy AICA Ribonucleotide Nasal Spray and buy AICAR Pre Mixed peptide. Buy AICA ribonucleotide from Pharma Lab Global today!


DISCLAIMER: All products sold by PharmaLabGlobal are for in-vitro research and laboratory use only. These products are not designed for use or consumption by humans or animals. Nothing on this Website is intended to diagnose, heal, treat, cure, mitigate or prevent disease. By purchasing from our Website the buyer accepts and acknowledges the risks involved with consumption and handling of these products. All articles and product information provided on this Website are for informational and educational purposes only. All products are to be handled by qualified and properly trained research or laboratory professionals only.

Additional information

Weight 0.01 kg
Dimensions 1 × 1 × 1 cm

50mg Vial, Kit = 50mg vial, bac water, syringes