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FOXO4-DRI pre-mixed pen 10mg is a senolytic peptide that disrupts the p53 gene, causing apoptosis in ageing cells. This peptide may lead to a disease-free life with future investigation by reducing senescent cell formation.
Pen Kit & Pre-Mixed Cartridge contains:
1 x Pre-Mixed Cartridge (The cartridge is pre mixed with the peptide vial of your choice and Bacteriostatic Water)
1 x Peptide Cartridge Pen
3 x Pen Needle Tips
1 x Pen Carry Case
Please note: Single 1, 2 & 3 Pre-mixed Cartridges do not come with a Pen Kit
£198.68 – £591.03
The protein FOXO4 has been altered to become FOXO4-D-Retro-Inverso. The alteration prolongs the half-life of the protein and allows it to interfere with regular FOXO4 function. Application of this protein has been associated with reduced senescent cells, improved organ function, and younger tissue “biological age” (references n.d.). The effects of FOXO4-DRI Pre-Mixed Pen 10mg include oxidative stress signalling, the cell cycle, and insulin. Animal studies have shown that this cell-penetrating peptide can counteract the effects of ageing.
A senolytic peptide called foxo4dri causes apoptosis in ageing cells by interfering with the p53 gene. With more research, this peptide may contribute to a life free from disease by preventing the production of senescent cells.
What are senescent cells?
More cells become senescent as we age, which means they are unable to divide or support their own tissues. These cells release harmful chemical signals that induce senescence in neighbouring cells, which can raise the risk of cancer, damage tissue, and create inflammation.
Laboratory studies have demonstrated that FOXO4 prevents the growth of these dangerous cells in animal models. It can even locate and destroy these cells within the bodies of test subjects.
Molecular Formula: C228H388N86O64
Sequence: H-LTLRKEPASEIAQSIL EAYSQNGWANRRSGGK RPPPRRRQRRKRG-OH
Molecular Weight: 5358.05 g/mol
Size: 1 Single mixed cartridge | 2 Pre mixed cartridges | 3 Pre mixed cartridges | Pen kit with 1 pre mixed cartridge
Tests for the foxo4 peptide were conducted on mice with accelerated hereditary ageing and naturally ageing animals. Following the mice’s rigorous chemotherapy treatments, the researchers discovered some fascinating findings. FOXO4-DRI Pre-Mixed Pen 10mg significantly reduced the harm caused by chemotherapy in both sets of rats. In the animal test subjects, the FOXO4 drug also reversed fur loss and improved liver and kidney function [1].
Neurodegenerative
It’s unclear exactly what causes age-related cognitive deterioration, such as Alzheimer’s. Neurodegenerative diseases have been connected to changes in proteasome activity. Prion disorders, Huntington’s, Parkinson’s, and early-onset dementia have all been related to disrupted proteasome activity. It’s unclear, though, if this is the main reason or just one of the contributing factors [2].
Also, proteasome function is impacted by Lou Gehrig’s disease, or ALS. Scientists have been investigating the possibility that exogenous FOXO protein could be beneficial in light of the finding that extracellular FOXO protein may aid in the treatment or prevention of neurodegenerative illnesses. At minimum, FOXO4-DRI Pre-Mixed Pen 10mg, a modified FOXO protein, may help reduce the progression of neurodegenerative disorders [3].
Heart disease
Also, proteasome function is impacted by Lou Gehrig’s disease, or ALS. Researchers have been investigating the possibility that exogenous FOXO protein could be beneficial in light of the finding that extracellular FOXO protein may aid in the treatment or prevention of neurodegenerative illnesses. At minimum, FOXO4-DRI Pre-Mixed Pen 10mg, a modified FOXO protein, may help reduce the progression of neurodegenerative disorders [4].
FOXO proteins support both autophagy and proteasome function. In certain tissues, lower levels of oxidation and protein damage result from elevated FOXO4 levels because they boost proteasome activity. FOXO4-DRI The heart’s natural housekeeping processes may be aided with Pre-Mixed Pen 10mg or a similar product, which could help reduce the effects of ageing on the heart’s capacity to pump blood throughout the body [5].
Anti-ageing
FOXO4 is beneficial to senescent or burdened cells. It binds to p53, which prevents the senescent cells from dying. The FOXO4-p53 interaction is blocked by DRI peptide. P53 triggers cell death by turning on apoptotic proteins. As a result, tissues can regenerate more fully by expelling aged cells. In tests, the DRI peptide extended the life span and promoted tissue regeneration in aged mice.
This is the period during which the body is active. It dwindles with age. A person’s health span can be extended by reducing biological tissue ageing. The older mice live longer, are more active, and have less impairment such as cardiac disease and musculoskeletal trouble .
The 10 mg FOXO4-DRI pre-mixed pen medicine is thought by specialists to be a possible treatment for age-related diseases, although animal research is still in its early stages.
In animal studies, it has been demonstrated that 10 mg of FOXO4-DRI Pre-Mixed pen increases apoptosis in senescent cells, enhancing tissue function and general wellbeing. Although the exact impact of FOXO4 DRI is unknown, the protein may have information on age-related disorders such as Alzheimer’s, heart conditions, and generalised cell senescence. The 10 mg FOXO4-DRI pre-mixed pen exhibits a good subcutaneous bioavailability and few adverse effects in mice.
[1] https://pubmed.ncbi.nlm.nih.gov/ 28340339/
[2] https://pubmed.ncbi.nlm.nih.gov/ 14556719/
[3] https://pubmed.ncbi.nlm.nih.gov/ 29428128/
[4] https://www.sciencedirect.com/ science/article/abs/pii/S000398610 1926633?via%3Dihub
[5] https://www.hindawi.com/ journals/omcl/2017/3494289/
[6] https://www.cell.com/cell/pdf/ S0092-8674 (17)30246-5.pdf
Pharma Lab Global is one of the best locations to purchase high purity FOXO4-DRI Pre-Mixed Pen 10mg for research. Pharma Lab Global is a trusted supplier of peptides and sarms worldwide. You have the option to buy FOX04-DRI Nasal Spray and buy FOX04-DRI Peptide Vial. Buy FOXO4-DRI Peptide from Pharma Lab Global today!
TO PURCHASE PRODUCTS FROM OUR WEBSITE YOU MUST BE AT LEAST 21 YEARS OF AGE.
DISCLAIMER: All products sold by Pharma Lab Global are for in-vitro research and laboratory use only. These products are not designed for use or consumption by humans or animals. Nothing on this Website is intended to diagnose, heal, treat, cure, mitigate or prevent disease. By purchasing from our Website the buyer accepts and acknowledges the risks involved with consumption and handling of these products. All articles and product information provided on this Website are for informational and educational purposes only. All products are to be handled by qualified and properly trained research or laboratory professionals only.
| Cartridge | 1 Single mixed cartridge, 2 Pre mixed cartridges, 3 Pre mixed cartridges, Pen kit with 1 pre mixed cartridge |
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TO PURCHASE PRODUCTS FROM OUR WEBSITE YOU MUST BE AT LEAST 21 YEARS OF AGE.
DISCLAIMER: All products sold by Pharma Lab Global are for in-vitro research and laboratory use only. These products are not designed for use or consumption by humans or animals. Nothing on this Website is intended to diagnose, heal, treat, cure, mitigate or prevent disease. By purchasing from our Website the buyer accepts and acknowledges the risks involved with consumption and handling of these products. All articles and product information provided on this Website are for informational and educational purposes only. All products are to be handled by qualified and properly trained research or laboratory professionals only.
